Results 91 to 100 of about 24,324,331 (382)

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

A surrogate modeling and adaptive sampling toolbox for computer based design [PDF]

, 2010
An exceedingly large number of scientific and engineering fields are confronted with the need for computer simulations to study complex, real world phenomena or solve challenging design problems.
Couckuyt, Ivo, Crombecq, Karel, Demeester, Piet, Dhaene, Tom, Gorissen, Dirk   +4 more
core  

A surrogate FRAX model for Mongolia

Archives of Osteoporosis
Abstract Summary A surrogate FRAX® model for Mongolia has been constructed using age- and sex-specific hip fracture rates for mainland China and age- and sex-specific mortality rates from Mongolia.
Jaalkhorol, M., Johansson, H., Avirmed, S., Dashtseren, A., Bruyère, O., Lorentzon, M., Harvey, N.C., McCloskey, E.V., Kanis, J.A.   +8 more
openaire   +5 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Support Vector Regression-Based Optimization for Triple Friction Pendulum Bearings: Achieving Computational Efficiency [PDF]

Journal of Soft Computing in Civil Engineering
Triple friction pendulum bearings (TFPBs) enhance the seismic resilience of base-isolated buildings. However, optimizing TFPB designs is computationally expensive, necessitating surrogate modeling techniques.
Mahnaz Akbarzaghi, Behrooz Ahmadi Nedushan, Hamed Tajammolian   +2 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

A constrained multi-objective surrogate-based optimization algorithm [PDF]

, 2014
Surrogate models or metamodels are widely used in the realm of engineering for design optimization to minimize the number of computationally expensive simulations.
Couckuyt, Ivo, Dhaene, Tom, Ferranti, Francesco, Singh, Prashant   +3 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Aero-structural characterization of wing planforms using machine learning

Advances in Aerodynamics
This study introduces a machine learning (ML) framework for efficient aero-structural characterization of wing planform shapes, addressing the computational challenges posed by traditional CFD and FEA methods.
Mehedi Hasan, Zhongmin Deng, Azad Khandoker   +2 more
doaj   +1 more source

On Design Mining: Coevolution and Surrogate Models [PDF]

Artificial Life, 2017
Design mining is the use of computational intelligence techniques to iteratively search and model the attribute space of physical objects evaluated directly through rapid prototyping to meet given objectives. It enables the exploitation of novel materials and processes without formal models or complex simulation.
Richard John Preen, Larry Bull
openaire   +3 more sources