Results 111 to 120 of about 223,298 (311)

Surrogate-assisted Genetic Programming with Simplified Models for Automated Design of Dispatching Rules

open access: yes, 2016
© 2013 IEEE. Automated design of dispatching rules for production systems has been an interesting research topic over the last several years. Machine learning, especially genetic programming (GP), has been a powerful approach to dealing with this design ...
Mengjie Zhang (8509230)
core   +1 more source

ML-Surrogate Model

open access: yes
This repository contains attachments related to the publication:**[Machine Learning Surrogate Optimization Framework for an Additively Manufactured, Linearly Polarized Metal Coaxial-to-Circular Waveguide Transition for Space Applications] ****Published in: ** [Engineering Applications of AI], [Volume xxx], [Issue yyy], [Year 2025], [Page Numbers zzz or
HASAN, MUHAMMAD FAHAD   +2 more
  +4 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Airfoil analysis and design using surrogate models

open access: yes, 2020
A study was performed to compare two different methods for generating surrogate models for the analysis and design of airfoils. Initial research was performed to compare the accuracy of surrogate models for predicting the lift and drag of an airfoil with
Michael, Nicholas Alexander
core  

Computational Optimisation of Urban Design Models: A Systematic Literature Review

open access: yesUrban Science
The densification of urban spaces globally has contributed to a need for design tools supporting the planning of more sustainable, efficient, and liveable cities.
JingZhi Tay   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A Review on Joint Models in Biometrical Research [PDF]

open access: yes, 2006
In some fields of biometrical research joint modelling of longitudinal measures and event time data has become very popular. This article reviews the work in that area of recent fruitful research by classifying approaches on joint models in three ...
Neuhaus, Anneke   +3 more
core   +1 more source

Assessment of Surrogate Models for Research on Resistance and Deformation of Repairs of the Human Meniscal Roots: Porcine or Older Human Models?

open access: yesApplied Sciences
Meniscal root repair is not routinely recommended for patients over 75 years old, yet surrogate age-unrestricted human or porcine models are used for its evaluation.
Alejandro Peña-Trabalon   +4 more
doaj   +1 more source

Recent Design Optimization Methods for Energy-Efficient Electric Motors and Derived Requirements for a New Improved Method—Part 1

open access: yesProceedings, 2018
Energy-efficient electric motors are gathering an increased attention since they are used in electric cars or to reduce operational costs, for instance.
Johannes Schmelcher   +4 more
doaj   +1 more source

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