Results 221 to 230 of about 15,304,814 (364)

Establishing a standard definition for child overweight and obesity worldwide: international survey

British medical journal, 2000
T. Cole, M. Bellizzi, K. Flegal, W. Dietz   +3 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Cohort profile: design and respondent characteristics for the longitudinal Survey of Trauma, Resilience and Opportunity Among Neighbourhoods in the Gulf (STRONG) cohort. [PDF]

BMJ Open
Harding AB, Parker AM, Parks V, Seelam R, Atshan S, Dormanesh A, Becker K, Ghosh Dastidar B, Ramchand R, Finucane ML, Slack T, Waldron-Moore PN, Ayer L.   +12 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Mind the Gap: Preliminary Insights Into Rural Australians' Experiences of Oral Health Care. [PDF]

Aust J Rural Health
Dangerfield F, Balla SB, Bracksley-O'Grady S, Dickson-Swift V.   +3 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Mental health and educational environments of university students during the post-Coronavirus Disease 2019 pandemic: A longitudinal study. [PDF]

PCN Rep
Tanaka M, Tanaka Y, Ohi K, Shioiri T.
europepmc   +1 more source

The Two Micron All Sky Survey (2MASS)

, 2006
M. Skrutskie, R. Cutri, R. Stiening, M. Weinberg, Simona Schneider, J. Carpenter, C. Beichman, R. Capps, T. Chester, J. Elias, J. Huchra, J. Liebert, C. Lonsdale, D. Monet, S. Price, P. Seitzer, T. Jarrett, J. Kirkpatrick, J. Gizis, E. Howard, T. Evans, J. Fowler, L. Fullmer, R. Hurt, R. Light, E. Kopan, K. Marsh, H. McCallon, R. Tam, S. V. van Dyk, S. Wheelock   +30 more
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Tectonic Characteristics of the Juyanhai Depression in the Yingen-Ejinaqi Basin, Inner Mongolia, China, Based on Gravity, Electrical, and Seismic Data

ACS Omega
Haihong Xu, Junlin Zhou, Xiaofeng Han, Yuhong Li, Jianshe Wei, Bo Song, Jizhong Shi, Wei Xu, Chunguan Zhang, Baowen Wang, Fei Zhao   +10 more
doaj   +1 more source