Results 51 to 60 of about 4,736,557 (326)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Prognostic Factors in Patients With Colorectal Cancer at Hospital Universiti Sains Malaysia

Asian Journal of Surgery, 2010
To determine the 5-year survival rate and prognostic factors for survival in patients with colorectal cancer treated at the Surgical Unit, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia.
Anis Kausar Ghazali, Kamarul Imran Musa, Nyi Nyi Naing, Zainal Mahmood   +3 more
doaj   +1 more source

Survival analysis of phacomorphic glaucoma at a tertiary hospital in North India

Taiwan Journal of Ophthalmology, 2022
Purpose: To report the intraocular pressure (IOP) and visual outcomes in patients operated for phacomorphic glaucoma in a developing country Methods: Patients undergone surgery for phacomorphic glaucoma between January 2015 and February 2018 with a ...
Richa Gupta, Surabhi Agrawal, Lokesh Chauhan   +2 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Epidemiological characteristics and survival analysis on patients with occupational pneumoconiosis in Zhejiang Province from 1987 to 2019

Frontiers in Public Health, 2022
ObjectiveTo evaluate risk factors affecting survival in patients diagnosed with pneumoconiosis and propose strategies to improve the quality of life in these patients.MethodsThe basic patient information was obtained from the pneumoconiosis report card ...
Hua Zou, Zhihao Shi, Yixin Zhang, Jiena Zhou, Xinglin Fang, Yijin Zhang, Yong Hu, Xiaoming Lou, Lifang Zhou   +8 more
doaj   +1 more source

Deep Kernel Survival Analysis and Subject-Specific Survival Time Prediction Intervals [PDF]

arXiv, 2020
Kernel survival analysis methods predict subject-specific survival curves and times using information about which training subjects are most similar to a test subject. These most similar training subjects could serve as forecast evidence. How similar any two subjects are is given by the kernel function.
arxiv  

The Association between Vitamin D Receptor Expression and Prolonged Overall Survival in Breast Cancer. [PDF]

, 2012
Summary In this study, we analyzed vitamin D receptor (VDR) expression and survival in a breast cancer patient cohort of 82 breast cancer patients. Immunohistochemical analysis was possible in 91.5% of the patients (75/82). Staining was evaluated using
Berger U, Berger U, Boecker W, Conde I, Eisman JA, Frampton RJ, Freake HC, Gombart AF, Jeschke U, Mason BH, Mylonas I, Remmele W, Ulmann A, Zinser GM   +13 more
core   +2 more sources

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

FEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr, Klaus Mayer, Raffael Schaffrath, Johannes Buchner, Ulrich Brinkmann   +4 more
wiley   +1 more source

Adult social position and sick leave: the mediating effect of physical workload

Scandinavian Journal of Work, Environment & Health, 2015
OBJECTIVE: This study aimed to quantify how much of the adult social gradient in sick leave can be attributed to the mediating role of physical workload while accounting for the role of childhood and adolescent social position and neuroticism.
Karina Corbett, Jon Michaeal Gran, Petter Kristensen, Ingrid Sivesind Mehlum   +3 more
doaj   +1 more source

Role of Depression and Social Isolation at Time of Waitlisting for Survival 8 Years After Heart Transplantation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundWe evaluated depression and social isolation assessed at time of waitlisting as predictors of survival in heart transplant (HTx) recipients. Methods and ResultsBetween 2005 and 2006, 318 adult HTx candidates were enrolled in the Waiting for a ...
Heike Spaderna, Armin Zittermann, Hermann Reichenspurner, Corinna Ziegler, Jacqueline Smits, Gerdi Weidner   +5 more
doaj   +1 more source