Results 61 to 70 of about 60,299 (235)
Aberrant Alternative Polyadenylation is Responsible for Survivin Up-regulation in Ovarian Cancer
Chinese Medical Journal, 2016 Background: Survivin is an oncoprotein silenced in normal mature tissues but reactivated in serous ovarian cancer (SOC). Although transcriptional activation is assumed for its overexpression, the long 3'-untranslated region (3'-UTR) in survivin gene ...
Xiang-Jun He +5 more
doaj +1 more source
Clinical correlation of nuclear survivin in esophageal squamous cell carcinoma [PDF]
, 2012 To examine the correlation of survivin (both total and nuclear survivin) with clinicopathological parameters of esophageal squamous cell carcinoma (ESCC) patients.
Chan, KW +10 more
core +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara +5 more
wiley +1 more source
Activation of Fms-like tyrosine kinase 3 signaling enhances survivin expression in a mouse model of rheumatoid arthritis. [PDF]
PLoS ONE, 2012 Survivin is known as an inhibitor of apoptosis and a positive regulator of cell division. We have recently identified survivin as a predictor of joint destruction in patients with rheumatoid arthritis (RA).
Sofia E M Andersson +5 more
doaj +1 more source
Down-regulation of Survivin enhances sensitivity to BPR0L075 in human cancer cells via caspase-independent mechanisms [PDF]
, 2008 Background: BPR0L075 [6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole] is a novel anti-cancer compound. It inhibits tubulin polymerization and induces mitochondrial-dependent apoptosis in various human cancer cells with different multi-
Chi-Yen Chang +5 more
core +1 more source
Lapatinib potentiates cytotoxicity of YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter [PDF]
, 1967 Adverse side effects of cancer agents are of great concern in the context of childhood tumors where they can reduce the quality of life in young patients and cause life-long adverse effects.
Brunak, Søren +8 more
core +3 more sources
Polish Gynaecology, 2015 Survivin is a member of the inhibitor of apoptosis protein (IAP) family which are selectively overexpressed in human neoplasms, and its expression has been shown to be connected with cell proliferation. We analyzed survivin expression in ovarian epithelial neoplasms to evaluate its role in the development of ovarian tumors.Immunohistochemistry assays ...
Danuta, Plewka +9 more
openaire +2 more sources
Survivine en cancérologie [PDF]
médecine/sciences, 2008 Decouverte il y a dix ans, Survivine orchestre a la fois le cycle et la mort cellulaire, deux fonctions particulierement deregulees dans les cellules cancereuses. Presente au cours du developpement embryonnaire, puis absente des tissus differencies adultes, Survivine est fortement exprimee dans la plupart des tumeurs.
Mathilde Romagnoli +3 more
openaire +1 more source
Food Safety and Health, EarlyView.Aloe vera‐derived biopolymers and nanoformulations enhance antimicrobial, antioxidant, and barrier functions in clean‐label edible coatings and films, whereas safety‐critical anthraquinone thresholds and regulatory constraints shape their translational potential.
Acharya Balkrishna +6 more
wiley +1 more source
Analytical Cellular Pathology, 2010 Background: Survivin is involved in the regulation of cell division and survival, two key processes in cancer. The majority of studies on survivin in colorectal cancer (CRC) have focused on protein expression and less is known about the expression of ...
Anna G. Antonacopoulou +9 more
doaj +1 more source