Results 71 to 80 of about 59,883 (231)
Clinical correlation of nuclear survivin in esophageal squamous cell carcinoma [PDF]
, 2012 To examine the correlation of survivin (both total and nuclear survivin) with clinicopathological parameters of esophageal squamous cell carcinoma (ESCC) patients.
Chan, KW +10 more
core +1 more source
Polish Gynaecology, 2015 Survivin is a member of the inhibitor of apoptosis protein (IAP) family which are selectively overexpressed in human neoplasms, and its expression has been shown to be connected with cell proliferation. We analyzed survivin expression in ovarian epithelial neoplasms to evaluate its role in the development of ovarian tumors.Immunohistochemistry assays ...
Danuta, Plewka +9 more
openaire +2 more sources
Survivine en cancérologie [PDF]
médecine/sciences, 2008 Decouverte il y a dix ans, Survivine orchestre a la fois le cycle et la mort cellulaire, deux fonctions particulierement deregulees dans les cellules cancereuses. Presente au cours du developpement embryonnaire, puis absente des tissus differencies adultes, Survivine est fortement exprimee dans la plupart des tumeurs.
Mathilde Romagnoli +3 more
openaire +1 more source
Phytochemical Analysis, EarlyView.ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek +3 more
wiley +1 more source
Journal of Experimental & Clinical Cancer Research, 2009 Background p53AIP1 is a potential mediator of apoptosis depending on p53, which is mutated in many kinds of carcinoma. High survivin expression in non-small cell lung cancer is related with poor prognosis.
Yamamoto Satoshi +6 more
doaj +1 more source
Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non-Small Cell Lung Cancer. [PDF]
, 2018 Purpose: The retinoblastoma tumor suppressor (RB), a key regulator of cell-cycle progression and proliferation, is functionally suppressed in up to 50% of non-small cell lung cancer (NSCLC).
Addya, Sankar +14 more
core +1 more source
Biomarkers of basal cell carcinoma resistance to methyl-aminolevulinate photodynamic therapy [PDF]
, 2019 This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Gilaberte, Yolanda +6 more
core +4 more sources
Survivin – The inconvenient IAP [PDF]
Seminars in Cell & Developmental Biology, 2015 Although technically a member of the Inhibitor of Apoptosis (IAP) gene family, survivin has consistently defied assumptions, refuted predictions and challenged paradigms. Despite its more than 5500 citations currently in Medline, the biology of survivin has remained fascinatingly complex, its exploitation in human disease, most notably cancer ...
openaire +2 more sources
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Expression of Survivin and Its Spliced Variants in Bladder Tumors as a Potential Prognostic Marker
Urology Journal, 2009 <p><strong>Introduction: </strong>Survivin, a novel inhibitor of apoptosis, is re-expressed in a vast majority of human cancers and is widely considered as a diagnostic marker of cancers.
Ardalan Ozhand +5 more
doaj