Results 41 to 50 of about 41,070 (225)
Stem Cell Research, 2014 The BIRC5 gene encodes the oncofetal protein SURVIVIN, as well as four additional splice variants (ΔEx3, 2B, 3B and 2α). SURVIVIN, an inhibitor of apoptosis, is also a chromosomal passenger protein (CPP).
Amber N. Mull +2 more
doaj +1 more source
Proteomics of Acute Myeloid Leukemia [PDF]
, 2007 Acute Myeloid Leukemia (AML) is characterized by specific cytogenetic aberrations that are strong determinants of prognostic outcome and therapeutic response.
Yaseen, Mumtaz
core +1 more source
Biotechnology & Biotechnological Equipment, 2019 Survivin is a bifunctional protein which regulates cell division and inhibits apoptosis. Survivin is a member of the inhibitor of apoptosis protein (IAP) family.
Nur Topyalin +6 more
doaj +1 more source
Immunohistochemical detection of survivin in canine lymphoma [PDF]
, 2010 Survivin is a member of the family of proteins known as “inhibitors of apoptosis proteins”. Survivin has a role in cellular decisions concerning division and survival and is frequently expressed in neoplastic cells.
Guscetti, Franco +13 more
core +1 more source
PLoS ONE, 2020 Breast cancer stem cells (BCSCs) express high levels of the anti-apoptotic protein, survivin. This study aimed to discover a natural active compound with anti-cancer properties that targeted survivin in human breast cancer stem cells.
Septelia Inawati Wanandi +6 more
doaj +1 more source
The Effect and Mechanism of Celecoxib in Hypoxia-Induced Survivin Up-Regulation in HUVECs
Cellular Physiology and Biochemistry, 2015 Background/Aims: To investigate the roles of hypoxia-inducible factor 1α (HIF-1α), cyclooxygenase-2 (Cox-2) and its product, Prostaglandin E2 (PGE2), in the mechanisms underlying hypoxia-induced survivin expression in human umbilical vein endothelial ...
Ning-ning Liu, Ning Zhao, Na Cai
doaj +1 more source
Activation of Fms-like tyrosine kinase 3 signaling enhances survivin expression in a mouse model of rheumatoid arthritis. [PDF]
PLoS ONE, 2012 Survivin is known as an inhibitor of apoptosis and a positive regulator of cell division. We have recently identified survivin as a predictor of joint destruction in patients with rheumatoid arthritis (RA).
Sofia E M Andersson +5 more
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Aven and Survivin Expression in Egyptian Acute Leukemia and Their Relation to Apoptosis [PDF]
, 2009 Background: Several anti apoptotic signals have been recently identified. Aven and Survivin are broadly expressed and are conserved in mammalian species. Patients and Methods: 39 AML and 25 ALL were tested.
Ayman Metwally +7 more
core
, 2016 (A) Heatmap of proteomics identification of mitochondrial proteins co-precipitated with an antibody to survivin (SVV) or control IgG from PC3 mitochondrial extracts. Two independent replicates per condition are shown. A fold enrichment in spectra counts (
M. Cecilia Caino (181113) +12 more
core +1 more source