Results 31 to 40 of about 6,323,337 (377)

Influence of Nitrogen on Grapevine Susceptibility to Downy Mildew

Plants, 2023
Downy mildew, caused by the obligate parasite Plasmopara viticola, is one of the most important threats to viticulture. The exploitation of resistant and susceptibility traits of grapevine is one of the most promising ways to increase the sustainability ...
Demetrio Marcianò, Valentina Ricciardi, Giuliana Maddalena, Annamaria Massafra, Elena Marone Fassolo, Simona Masiero, Piero Attilio Bianco, Osvaldo Failla, Gabriella De Lorenzis, Silvia Laura Toffolatti   +9 more
doaj   +1 more source

Mapping the genetic architecture of gene expression in human liver [PDF]

, 2008
Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order disease traits.
Avila-Campillo, I, Chudin, E, Derry, J, Drake, TA, Guengerich, FP, GuhaThakurta, D, Hao, K, Johnson, JM, Kasarskis, A, Kruger, MJ, Lamb, J, Lum, PY, Lusis, AJ, Mehrabian, M, Millstein, J, Molony, C, Rohl, CA, Rushmore, TH, Schadt, EE, Schuetz, E, Sieberts, S, Smith, RC, Storey, JD, Strom, SC, Suver, C, Ulrich, R, Van Nas, A, Wang, S, Yang, X, Zhang, B, Zhu, J   +30 more
core   +3 more sources

Exploring New Routes for Genetic Resistances to Potyviruses: The Case of the Arabidopsis thaliana Phosphoglycerates Kinases (PGK) Metabolic Enzymes

Viruses, 2022
The development of recessive resistance by loss of susceptibility is a consistent strategy to combat and limit damages caused by plant viruses. Susceptibility genes can be turned into resistances, a feat that can either be selected among the plant’s ...
Mamoudou Diop, Jean-Luc Gallois
doaj   +1 more source

Inactivation of tomato WAT1 leads to reduced susceptibility to Clavibacter michiganensis through downregulation of bacterial virulence factors

Frontiers in Plant Science, 2023
Tomato bacterial canker caused by Clavibacter michiganensis (Cm) is considered to be one of the most destructive bacterial diseases of tomato. To date, no resistance to the pathogen has been identified. While several molecular studies have identified (Cm)
Eleni Koseoglou, Eleni Koseoglou, Katharina Hanika, Mas M. Mohd Nadzir, Wouter Kohlen, Jan M. van der Wolf, Richard G. F. Visser, Yuling Bai   +7 more
doaj   +1 more source

Correlation of ciprofloxacin resistance with the AdeABC efflux system in Acinetobacter baumannii clinical isolates [PDF]

, 2014
Background: Acinetobacter baumannii is one of the most important pathogens capable of colonization in burn patients, leading to drug-resistant wound infections.
Ardebili, A., Lari, A.R., Talebi, M.
core   +1 more source

Plant Disease Susceptibility Genes? [PDF]

The Plant Cell, 2002
A recent search of the ISI Web of Science identified 524 documents related to “plant disease resistance” and just 1 match for the phrase “plant disease susceptibility.” This does not mean that scientists are not engaged in the study of what makes plants susceptible to disease.
openaire   +2 more sources

A transcriptome-wide association study of high grade serous epithelial ovarian cancer identifies novel susceptibility genes and splice variants

Nature Genetics, 2019
We sought to identify susceptibility genes for high-grade serous ovarian cancer (HGSOC) by performing a transcriptome-wide association study of gene expression and splice junction usage in HGSOC-relevant tissue types (N = 2,169) and the largest genome ...
A. Gusev, K. Lawrenson, Xianzhi Lin, P. Lyra, S. Kar, K. Vavra, Felipe Segato, M. A. Fonseca, Janet M. Lee, T. Pejovic, Gang Liu, B. Karlan, M. Freedman, H. Noushmehr, A. Monteiro, P. Pharoah, B. Pasaniuc, S. Gayther   +17 more
semanticscholar   +1 more source

Single-Cell RNA Sequencing Reveals the Expansion of Cytotoxic CD4+ T Lymphocytes and a Landscape of Immune Cells in Primary Sjögren’s Syndrome

Frontiers in Immunology, 2021
ObjectivePrimary Sjögren’s syndrome (pSS) is a systemic autoimmune disease, and its pathogenetic mechanism is far from being understood. In this study, we aimed to explore the cellular and molecular mechanisms that lead to pathogenesis of this disease ...
Xiaoping Hong, Xiaoping Hong, Shuhui Meng, Donge Tang, Tingting Wang, Liping Ding, Haiyan Yu, Heng Li, Dongzhou Liu, Yong Dai, Min Yang   +10 more
doaj   +1 more source

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation [PDF]

, 2016
We conducted a genome-wide association study (GWAS) on multiple sclerosis (MS) susceptibility in German cohorts with 4888 cases and 10,395 controls. In addition to associations within the major histocompatibility complex (MHC) region, 15 non-MHC loci ...
Andlauer, TF, Antony, G, Arloth, J, Bayas, A, Bechmann, L, Berger, K, Berthele, A, Bertram, L, Bettecken, T, Binder, EB, Buck, D, Carrillo-Roa, T, Chan, A, Cucca, F, Czamara, D, Dankowski, T, Franke, A, Gasperi, C, Gieger, C, Gold, R, Graetz, C, Haas, J, Hecker, M, Hemmer, B, Herms, S, Homuth, G, Infante-Duarte, C, Ising, M, Jöckel, KH, Kacprowski, T, Kloiber, S, Knop, M, Kümpfel, T, Laudes, M, Lichtner, P, Lieb, W, Lill, CM, Limmroth, V, Linker, RA, Loleit, V, Lucae, S, Luessi, F, Meitinger, T, Meuth, SG, Moebus, S, Mulas, A, Mühlau, M, Müller-Myhsok, B, Müller-Nurasyid, M, Nischwitz, S, Nöthen, MM, Paul, F, Petersmann, A, Pitzalis, M, Porcu, E, Pütz, M, Radivojkov-Blagojevic, M, Rawal, R, Ruck, T, Salmen, A, Scheinhardt, MO, Schminke, U, Sidore, C, Stangel, M, Stellmann, JP, Strauch, K, Stürner, KH, Tackenberg, B, Then Bergh, F, Tumani, H, Völzke, H, Waldenberger, M, Warnke, C, Weber, F, Weber, P, Wellmann, J, Wiendl, H, Wildemann, B, Zara, I, Zettl, UK, Ziegler, A, Ziemann, U, Zipp, F, Zoledziewska, M   +83 more
core   +2 more sources

Identifying breast cancer susceptibility genes – a review of the genetic background in familial breast cancer

Acta oncologica, 2019
Introduction: Heritage is the most important risk factor for breast cancer. About 15–20% of breast cancer is familial, referring to affected women who have one or more first- or second-degree relatives with the disease.
Camilla Wendt, S. Margolin
semanticscholar   +1 more source