Results 41 to 50 of about 6,323,337 (377)

The genetic basis of onset age in schizophrenia: evidence and models

Frontiers in Genetics, 2023
Schizophrenia is a heritable neurocognitive disorder affecting about 1% of the population, and usually has an onset age at around 21–25 in males and 25–30 in females.
Na Zhan, Pak C. Sham, Pak C. Sham, Pak C. Sham, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Simon S. Y. Lui   +11 more
doaj   +1 more source

Family history of any cancer for childhood leukemia patients in Sweden

eJHaem, 2021
Acute lymphoblastic leukemia (ALL) is the most common childhood leukemia, while the other types, acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), and chronic myeloid leukemia (CML) are much rarer.
Xinjun Li, Kristina Sundquist, Jan Sundquist, Asta Försti, Kari Hemminki   +4 more
doaj   +1 more source

Interplay between carotenoids, abscisic acid and jasmonate guides the compatible rice-Meloidogyne graminicola interaction [PDF]

, 2017
In this study, we have characterized the role of carotenoids and chlorophyll in the compatible interaction between the sedentary root knot nematode (RKN) Meloidogyne graminicola and the monocot model plant rice (Oryza sativa). Previous transcriptome data
Demeestere, Kristof, Gheysen, Godelieve, Haeck, Ashley, Kyndt, Tina, Nahar, Kamrun, Verbeek, Ruben   +5 more
core   +2 more sources

Susceptibility genes for complex epilepsy [PDF]

Human Molecular Genetics, 2005
Common idiopathic epilepsies are, clinically and genetically, a heterogeneous group of complex seizure disorders. Seizures arise from periodic neuronal hyperexcitability of unknown cause. The genetic component is mostly polygenic, where each susceptibility gene in any given individual is likely to represent a small component of the total heritability ...
Mulley, J., Scheffer, I., Harkin, L., Berkovic, S., Dibbens, L.   +4 more
openaire   +4 more sources

Pathogenic and likely pathogenic variants in PALB2, CHEK2, and other known breast cancer susceptibility genes among 1054 BRCA‐negative Hispanics with breast cancer

Cancer, 2019
Breast cancer (BC) is the most common cancer and related cause of mortality among Hispanics, yet susceptibility has been understudied. BRCA1 and BRCA2 (BRCA) mutations explain less than one‐half of hereditary BC, and the proportion associated with other ...
J. Weitzel, S. Neuhausen, Aaron W Adamson, S. Tao, C. Ricker, Asaf Maoz, M. Rosenblatt, Bita Nehoray, S. Sand, L. Steele, G. Unzeitig, N. Feldman, Amie M. Blanco, D. Hu, S. Huntsman, D. Castillo, C. Haiman, T. Slavin, E. Ziv   +18 more
semanticscholar   +1 more source

Mutation Frequency in Main Susceptibility Genes Among Patients With Head and Neck Paragangliomas

Frontiers in Genetics, 2020
Head and neck paragangliomas (HNPGLs) are rare neuroendocrine tumors that have a high degree of heritability and are predominantly associated with mutations in ten genes, such as SDHx, SDHAF2, VHL, RET, NF1, TMEM127, MAX, FH, MEN2, and SLC25A11 ...
Anastasiya V. Snezhkina, Maria S. Fedorova, Vladislav S. Pavlov, Dmitry V. Kalinin, Alexander L. Golovyuk, Elena A. Pudova, Zulfiya G. Guvatova, Nataliya V. Melnikova, Alexey A. Dmitriev, George S. Razmakhaev, Andrey A. Poloznikov, Galina S. Alekseeva, Andrey D. Kaprin, George S. Krasnov, Anna V. Kudryavtseva   +14 more
doaj   +1 more source

Exploration of Lung Cancer-Related Genetic Factors via Mendelian Randomization Method Based on Genomic and Transcriptomic Summarized Data

Frontiers in Cell and Developmental Biology, 2021
Lung carcinoma is one of the most deadly malignant tumors in mankind. With the rising incidence of lung cancer, searching for the high effective cures become more and more imperative.
Nitao Cheng, Xinran Cui, Chen Chen, Changsheng Li, Jingyu Huang   +4 more
doaj   +1 more source

Frequency of Germline Mutations in Cancer Susceptibility Genes in Malignant Mesothelioma.

Journal of Clinical Oncology, 2018
PURPOSE The aim of the current study was to determine the prevalence and clinical predictors of germline cancer susceptibility mutations in patients with malignant mesothelioma (MM).
Vasiliki Panou, Meghana Gadiraju, Arthur Wolin, C. Weipert, Emily Skarda, A. Husain, J. Patel, B. Rose, Shannon R Zhang, Madison Weatherly, V. Nelakuditi, Amy E. Knight Johnson, Maria L. Helgeson, David Fischer, A. Desai, N. Sulai, Lauren L. Ritterhouse, O. Røe, K. Turaga, D. Huo, J. Segal, Sabah Kadri, Zejuan Li, H. Kindler, J. Churpek   +24 more
semanticscholar   +1 more source

Genetic Factors Contributing to the Susceptibility of Development of Prion Diseases [PDF]

, 2017
This paper won an honorable mention writing flag award in the research category. Claire Culbertson, writing for Katherine Bruner’s BIO 325L class, “Lab Experience in Genetics”.Bruner, KatherineUndergraduate ...
Culbertson, Claire
core   +1 more source

Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease

Hepatology Communications, 2019
Coronary artery disease (CAD) is the principal cause of death in patients with nonalcoholic fatty liver disease (NAFLD). The aim of the present study was to investigate whether NAFLD is causally involved in the pathogenesis of CAD.
M. Brouwers, N. Simons, C. Stehouwer, G. Koek, N. Schaper, A. Isaacs   +5 more
semanticscholar   +1 more source