Results 51 to 60 of about 6,323,337 (377)

HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory Failure

Frontiers in Immunology, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (COVID-19) was announced as an outbreak by the World Health Organization (WHO) in January 2020 and as a pandemic in March 2020.
Seik-Soon Khor, Yosuke Omae, Nao Nishida, Masaya Sugiyama, Noriko Kinoshita, Tetsuya Suzuki, Michiyo Suzuki, Satoshi Suzuki, Shinyu Izumi, Masayuki Hojo, Norio Ohmagari, Masashi Mizokami, Katsushi Tokunaga   +12 more
doaj   +1 more source

Susceptibility Genes in Thyroid Autoimmunity [PDF]

Journal of Immunology Research, 2005
The autoimmune thyroid diseases (AITD) are complex diseases which are caused by an interaction between susceptibility genes and environmental triggers. Genetic susceptibility in combination with external factors (e.g. dietary iodine) is believed to initiate the autoimmune response to thyroid antigens.
Yoshiyuki Ban, Yaron Tomer
openaire   +3 more sources

Multigene panel sequencing of established and candidate melanoma susceptibility genes in a large cohort of Dutch non‐CDKN2A/CDK4 melanoma families

International Journal of Cancer, 2019
Germline mutations in the major melanoma susceptibility gene CDKN2A explain genetic predisposition in only 10–40% of melanoma‐prone families. In our study we comprehensively characterized 488 melanoma cases from 451 non‐CDKN2A/CDK4 families for mutations
T. Potjer, Sander Bollen, Anneliese Grimbergen, R. van Doorn, N. Gruis, C. V. van Asperen, F. Hes, N. van der Stoep   +7 more
semanticscholar   +1 more source

Susceptibility Is New Resistance: Wheat Susceptibility Genes and Exploitation in Resistance Breeding

Agriculture, 2022
Adapted pathogens and pests seriously threaten global wheat production. During pathogen and pest infections, wheat susceptibility (S) genes are exploited to support the compatibility of wheat with pathogens and pests.
Mengmeng Li, Zige Yang, Cheng Chang
doaj   +1 more source

Resistance risk assessment of the novel complex II inhibitor pyflubumide in the polyphagous pest Tetranychus urticae [PDF]

, 2020
Pyflubumide is a novel selective carboxanilide acaricide that inhibits mitochondrial complex II of spider mite species such as Tetranychus urticae. We explored the baseline toxicity and potential cross-resistance risk of pyflubumide in a reference panel ...
Fotoukkiaii, Seyedeh Masoumeh, Mermans, Catherine, Van Leeuwen, Thomas, Wybouw, Nicky   +3 more
core   +1 more source

DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]

, 2010
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams, Afanasev, Alina E. Gorna, Aly, Arnold, Bacon, Banu, Bergval, Betts, Boshoff, Boshoff, Bostanabad, Burney, Capelli, Chan, Chan, Cheng, Cooper, Cubillos-Ruiz, Darwin, Darwin, Das, Davis, Dos Vultos, Dubnau, Durbach, Farnia, Fennelly, Filliol, Fleischmann, Flint, Fontan, Friedberg, Frischkorn, Fu, Fu, Gaynor, Gordhan, Graham, Grishko, Guthlein, Hampshire, Hazbon, Hughes, Jain, Jaroslaw Dziadek, Jiao, Kapur, Karakousis, Karakousis, Karunkaran, Katti, Kesavan, Kim, Ko, Ko, Korycka-Machala, Krokan, Kurthkoti, Kurthkoti, Lari, Lever, Loudon, MacMicking, Malshetty, Martinez, Mokrousov, Moller, Movahedzadeh, Mulder, Munoz-Elias, Muttucumaru, Nguyen, Niemann, Nikolayevskyy, Nouvel, O'sullivan, Olano, Peccia, Peccia, Pitcher, Rachman, Rachman, Rad, Ramaswamy, Richard P. Bowater, Riley, Saito, Sander, Sassetti, Sassetti, Saunders, Schnappinger, Schwab, Sherman, Sinha, Sinha, Smeulders, Springer, Srivastava, Stephanou, Talaat, Talaat, Tang, Tsai, Venkatesh, Vilcheze, Voskuil, Voskuil, Waddell, Wanner, Warner, Weikert, Wiid, Wiseman, World Health Organization, Zaczek, Zainuddin   +117 more
core   +1 more source

Tumor Susceptibility Genes

Cancer Control, 1998
Cancer develops and progresses as the result of accumulated genetic damage or mutations. These mutations are most commonly described as either oncogenes, which positively regulate cell growth, or tumor suppressor genes, which negatively regulate cell growth.
openaire   +2 more sources

Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.

Schizophrenia bulletin, 2018
Genome-wide association studies (GWASs) have identified >100 susceptibility loci for schizophrenia (SCZ) and demonstrated that SCZ is a polygenic disorder determined by numerous genetic variants but with small effect size.
M. Ikeda, A. Takahashi, Y. Kamatani, Y. Momozawa, Takeo Saito, Kenji Kondo, Ayu Shimasaki, Kohei Kawase, T. Sakusabe, Y. Iwayama, T. Toyota, Tomoyasu Wakuda, M. Kikuchi, N. Kanahara, H. Yamamori, Y. Yasuda, Yuichiro Watanabe, Satoshi Hoya, B. Aleksic, I. Kushima, H. Arai, M. Takaki, K. Hattori, H. Kunugi, Y. Okahisa, T. Ohnuma, N. Ozaki, T. Someya, R. Hashimoto, T. Yoshikawa, M. Kubo, N. Iwata   +31 more
semanticscholar   +1 more source

Association between 15 known or potential breast cancer susceptibility genes and breast cancer risks in Chinese women

Cancer Biology & Medicine, 2022
Objective: There are many hereditary breast cancer patients in China, and multigene panel testing has been a new paradigm of genetic testing for these patients and their relatives.
Fenfen Fu, Dongjie Zhang, Li Hu, Senthil Sundaram, Dingge Ying, Ying Zhang, Shuna Fu, Juan Zhang, Lu Yao, Ye Xu, Yuntao Xie   +10 more
doaj   +1 more source

Turning Susceptibility into Strength: A New Era of Durable Resistance in Plants Through Genome Editing

Plants
In plants, resistance genes (R) are key players in combatting diseases caused by various phytopathogens. Typically, resistance relies on detecting a single pathogen-derived molecular pattern.
Shallu Thakur, Simranjot Kaur, Sudeep Adhikari, Prerna Sabharwal, Yuqing Fu, Geoffrey Meru   +5 more
doaj   +1 more source