Results 131 to 140 of about 220,364 (303)
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Status of Concentrated Solar Power Plants Installed Worldwide: Past and Present Data
Clean TechnologiesSolar energy is not only the most abundant energy on earth but it is also renewable. The use of this energy is expanding very rapidly mainly through photovoltaic technology.
Sylvain Rodat, Richard Thonig
doaj +1 more source
Translation Mechanisms in Socio-Technical Niches. A case study of Dutch river management [PDF]
This paper makes three contributions to the field of transition research. First, it sheds light on how the concept of translation can contribute to a better understanding of agency in niche development.
Geert P.J. Verbong +3 more
core
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Strategic Niche Management (SNM) beyond sustainability. An exploration of key findings of SNM through the lens of ICT and privacy [PDF]
Recently the governance of socio-technical transitions to sustainability is gaining attention in the field of innovation studies. One particular approach is that of Strategic Niche Management (SNM), which advocates the creation of protected space to ...
Q.C. van Est +2 more
core
Sustainable bioplastics manufacturing from renewable sources
FEBS Open Bio, EarlyView.Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
Making Sustainability Transitions Appealing: The Need for Alternative Narratives in France
Blue PapersSustainability transitions offer opportunities to rethink and improve society, such as by improving well-being, reducing inequalities and reconnecting with nature.
Maëlle Salzinger
doaj +1 more source