Results 61 to 70 of about 709,395 (249)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Disaster Risk Reduction Including Climate Change Adaptation Over South Asia: Challenges and Ways Forward

International Journal of Disaster Risk Science, 2018
South Asia is vulnerable to a variety of hydrometeorological hazards, which are often cross-boundary in nature. Climate change is expected to influence many of these hazards.
Rajesh K. Mall, Ravindra K. Srivastava, Tirthankar Banerjee, Om Prakash Mishra, Diva Bhatt, Geetika Sonkar   +5 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Circular Economy and Cascading: Towards a Framework

Resources, Conservation & Recycling: X, 2020
The principle of cascading, the sequential and consecutive use of resources, is a potential method to create added value in circular economy (CE) practices.
Kieran Campbell-Johnston, Walter J.V. Vermeulen, Denise Reike, Sabrina Brullot   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Life Cycle Assessment of Valorizing Waste Polyethylene and Coconut Shells Into Activated Carbon Polymer Flakes

International Journal of Chemical Engineering
Polyethylene (PE) accounts for approximately 40% of total global plastic production, yet PE waste remains an underutilized feedstock. Meanwhile, activated carbon (AC) derived primarily from coconut shells (CS), the most popular source, is usually ...
Junaid Saleem, Moghal Zubair Khalid Baig, Furqan Tahir, Gordon McKay   +3 more
doaj   +1 more source

Gender disparities in agricultural land access and cashew farming participation in Kintampo South District, Ghana

Journal of Agriculture and Rural Development in the Tropics and Subtropics
This study examines gender disparities in access to agricultural land and participation, using a sample of 200 cashew farmers in the Kintampo South District of Ghana and descriptive statistical analysis.
Daniella Delali Sedegah
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Targeting Irrigation Expansion to Address Sustainable Development Objectives: A Regional Farm Typology Approach [PDF]

, 2021
Matthew C. LaFevor, A.N. Frake, Stéphane Couturier   +2 more
openalex   +1 more source