Results 101 to 110 of about 177,033 (306)

The use of cheese whey powder in the cultivation of protein-rich filamentous fungal biomass for sustainable food production [PDF]

Cheese whey is an industrial by-product that is generated in excess during the cheese production process in the dairy industry. Despite the potential utility of whey, it continues to pose environmental threats in the industry.
Taherzadeh, Mohammad J, Wijayarathna, E.R. Kanishka B., Yüceer, Yonca Karagül,, Taherzadeh, Mohammad J., Wijayarathna, E.R. Kanishka B.,, Swarnima Agnihotri, Agnihotri, Swarnima,, Taherzadeh, Mohammad J,, Karagül Yüceer, Yonca, Sar, Taner, Agnihotri, Swarnima, E. R. Kanishka B. Wijayarathna, Taner Sar, Wijayarathna, E. R. Kanishka B., Kaya, Burcu,, Mohammad J. Taherzadeh, Sar, Taner,, Yüceer, Yonca Karagül, Kaya, Burcu, Yonca Karagül Yüceer, Burcu Kaya   +20 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Restoring Pre-Industrial CO2 Levels While Achieving Sustainable Development Goals

, 2020
Unless humanity achieves United Nations Sustainable Development Goals (SDGs) by 2030 and restores the relatively stable climate of pre-industrial CO2 levels (as early as 2140), species extinctions, starvation, drought/floods, and violence will exacerbate
Michael D. Chambers, Anthony T. Jones, Mark E. Capron, Jang K. Kim, Scott C. James, Mohammed A. Hasan, Graham Harris, Antoine de Ramon N’Yeurt, Martin T. Sherman, Charles Yarish, Rae Fuhrman, Don Piper, Jim R. Stewart, Reginald B. Blaylock   +13 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Protein-based aerogels: processing and morphology

, 2020
Aerogels, partially or fully based on proteins, are emerging as promising sustainable biomaterials for a variety of applications, particularly in medicine and biosciences.
Sarah Fitzpatrick (6192197), Mark Staiger (15402326), Santanu Deb-Choudhury (755305), Steve Ranford (15396128)   +3 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Alternative proteins; A path to sustainable diets and environment

Current Research in Food Science
With a growing global population and the resulting pressure on natural resources, the supply of high-value protein has become increasingly limited. The rise of environmental and ethical concerns has led to the emergence of meat analogues as a credible alternative to traditional animal-derived meat.
Shima Jafarzadeh, Zeinab Qazanfarzadeh, Mahsa Majzoobi, Samira Sheiband, Nazila Oladzadabbasabad, Yasaman Esmaeili, Colin J. Barrow, Wendy Timms   +7 more
openaire   +3 more sources

Effect of Particle Size on the Physical Properties of PLA/Potato Peel Composites

Compounds
In recent years, agricultural by-product fillers have been investigated in composites to influence the physical properties of the packaging material, increase biodegradability, and reduce costs.
Katharina Miller, Corina L. Reichert, Myriam Loeffler, Markus Schmid   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A

Nature Communications
More than one percent of people have epilepsy worldwide. Levetiracetam (LEV) is a successful new-generation antiepileptic drug (AED), and its derivative, brivaracetam (BRV), shows improved efficacy.
Atsushi Yamagata, Kaori Ito, Takehiro Suzuki, Naoshi Dohmae, Tohru Terada, Mikako Shirouzu   +5 more
doaj   +1 more source