Results 111 to 120 of about 4,740,554 (399)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Microscopic mechanism and predicting calculation on mechanical properties of basalt fiber modified 3D printing cement-based materials

open access: yesCase Studies in Construction Materials
This study focuses on the modification and intelligent-digital control of 3D printing materials. Based on the significant effect of basalt fiber in improving toughness, the influence mechanism of basalt fiber substitution rate, length and other factors ...
Ben Li   +4 more
doaj   +1 more source

THE INFLUENCE OF PUBLIC PARTICIPATION ON SUSTAINABLE TRANSPORTATION AND REGIONAL DEVELOPMENT IN MEDAN

open access: yesIndonesian Journal of Geography, 2013
Sustainable transportation becomes very important in a certain town since it can influence the development of the town itself. One of the sustainable transportations is angkot (urban public transportation). Urban public transportation is one of the means
Hairulsyah .
doaj   +1 more source

A New Method for Designing Dense Skeleton Asphalt Mixture Based on Meso Parameter

open access: yesAdvances in Civil Engineering, 2020
At present, research on the internal structures of asphalt mixtures has mostly focused on the statistical analysis of their mesostructural components such as aggregates, voids, and asphalt mortars, in addition to the verification of the mechanical ...
Liwan Shi   +5 more
doaj   +1 more source

Sustainable Transportation and Urban Development [PDF]

open access: yes, 2014
The challenges facing transportation planners have grown continuously over the years owing to mounting problems of congestion, concerns with environmental degradation and global warming, enhanced awareness of safety, and the increasing complexity of ...
Shefer, Daniel
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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