Results 81 to 90 of about 1,435,203 (288)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Acta PsychologicaSustained attention is important for optimal neurobehavioral performance, but many biological and environmental factors (e.g., circadian rhythm, distraction, etc.) may cause sustained attention deficits.It has been suggested that mastication (chewing ...
Devon A. Hansen +2 more
doaj +1 more source
Attention and Neurocognitive Impairment in ADHD
Pediatric Neurology Briefs, 2007 Specific executive functions (EFs) and attention deficit patterns in ADHD subtypes were studied in 50 boys (ages 8-14 years, mean 10.42) with ADHD and 44 controls, at the University of Rome, Italy.
J Gordon Millichap
doaj +1 more source
Boys with oppositional defiant disorder/conduct disorder show impaired adaptation during stress: an executive functioning study [PDF]
, 2017 Evidence for problems in executive functioning (EF) in children with oppositional defiant disorder/conduct disorder (ODD/CD) is mixed and the impact stress may have on EF is understudied.
de Wied, Minet +4 more
core +4 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Designing Interaction to Support Sustained Attention
, 2023 The impact of digital technology on human cognition has become a topic of significant interest in recent years, with various studies highlighting the adverse effects on cognition, particularly attention. While the negative impact of digital applications on our attentional processes is well-documented, practical solutions to mitigate these detrimental ...
Hacioglu, Naile +2 more
openaire +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
ATTENTION AND SCHOOL SUCCESS: The Long-Term Implications of Attention for School Success among Low-Income Children [PDF]
This study examined the longitudinal associations between sustained attention in preschool and children’s school success in later elementary school within a low-income sample (N = 2,403). Specifically, two facets of sustained attention (focused attention
Anne Martin +2 more
core