Results 81 to 90 of about 2,204,672 (307)

Dextran and its potential use as tablet excipient [PDF]

open access: yes, 2015
Dextrans are a class of carbohydrate polymers extensively applied in pharmaceutical applications, particularly as drug conjugate macromolecular carriers or drug delivery systems.
D. R. Perinelli   +14 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Sustained-release pregabalin with methylcobalamin in neuropathic pain: an Indian real-life experience

open access: yes, 2013
Yasmin U Dongre, Onkar C Swami Unichem Laboratories Ltd, Unichem Bhavan, Mumbai, India Introduction: Neuropathic pain is intense in nature and difficult to manage. Thus, the primary goal is maximum relief from pain.
Dongre YU, Swami OC
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Sustained release of silver from periodontal wafers for treatment of periodontitis

open access: yes, 2000
Periodontal wafers intended to treat the underlying infections in patients with periodontitis have been developed. The wafers consist of poly(lactic-co-glycolic acid) as a primary bioerodible polymeric component, poly(ethylene glycol) as a plasticizer ...
Lev E Bromberg   +17 more
core   +1 more source

Formulation of Sustained Release Hydrophilic Matrix Tablets of Tolcapone with the Application of Sedem Diagram: Influence of Tolcapone’s Particle Size on Sustained Release

open access: yes, 2020
Hydrophilic matrix tablets are a type of sustained release dosage form characterized by distributing a drug in a matrix that is usually polymeric. Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase.
Raul Insa Boronat   +8 more
core   +1 more source

DEVELOPMENT AND IN VITRO ASSESSMENT OF GASTRO-RETENTIVE BILAYER FLOATING TABLET FOR MANAGING HYPERTENSION IN ACUTE CONDITIONS [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University
Background: This study disseminates the formulation and in vitro assessment of bilayer floating tablets designed to be retained in the stomach, delivering a combination of amlodipine besylate and atenolol.
Aparna Datta   +3 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Survey of common factors to determine suitability for work release

open access: yes, 1969
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF cover (viewed on June 20, 2016)."Work release

core  

Development of indapamide sustained release tablet using methocel K15 MCR and a comparative study with a reference product

open access: yes, 2008
Indapamide, a low-dose thiazide-type diuretic, is used for the treatment of essential hypertension. In this study, we developed an indapamide sustained release formulation using Methocel K15 MCR (a modified hydroxypropyl methylcellulose), lactose and ...
Wahed, M.I.I.   +6 more
core   +1 more source

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