Results 141 to 150 of about 5,883,314 (302)

Very rapid virologic response and early HCV response kinetics, as quick measures to compare efficacy and guide a personalized response-guided therapy

, 2016
Mostafa Yakoot,1,2 Alaa M Abdo,3 Ahmed Yousry,4,5 Sherine Helmy6 1Green Clinical Research Center, 2Abbas Helmy Clinics, 3Tropical Medicine and Hepatology Department, Alexandria Faculty of Medicine, 4Microbiology Department, High Institute of Public ...
Yousry A, Helmy S, Abdo AM, Yakoot M
core  

Nutrimental Determinants of Chronological Aging and Competitiveness in the snf1Δ Warburg Model

Yeast, EarlyView.
Deletion of SNF1 in Saccharomyces cerevisiae alters chronological aging in a nutrient‐dependent manner, shortening lifespan under low‐nutrient conditions and extending it under high‐glucose and high‐amino‐acid conditions. Under nutrient‐rich conditions, the snf1∆ strain also showed an approximately 2‐log increase in competitiveness relative to the wild
Abigail Correa‐Olivares, Amanda de la Caridad Lahera Champagne, Alma Delia Bertadillo‐Jilote, Karla I. Lira‐de Leon, David G. Garcia‐Gutierrez, Gerardo M. Nava, Vanessa Sanchez‐Quezada, Luis Alberto Madrigal‐Perez   +7 more
wiley   +1 more source

Eradicating chronic Hepatitis C Viraemia : lessons learnt during the last decade [PDF]

, 2005
Over the last decade a better understanding of the mechanism for immune disposal of hepatocytes infected with the Hepatitis C virus enabled the design of antiviral regimens with increasing efficacy.
Pullicino, Edgar
core  

Virological response to PEGIFN/RBV by PNPLA3-SNP and IL28B-SNP.

, 2015
Virologic response rates (rapid virological response, complete early virological response and sustained virological response) to PEGIFN/RBV by PNPLA3-SNP and IL28B-SNP; reported as number (percentage) of patients; Abbreviations: PNPLA3 (patatin-like ...
Mattias Mandorfer (584776), Michael Trauner (124235), Thomas Reiberger (143056), Bernhard Scheiner (829816), Theresa Bucsics (654542), Peter Ferenci (659380), Philipp Schwabl (635845), Maximilian C. Aichelburg (790271), Simona Bota (654541), Katharina Grabmeier-Pfistershammer (322059), Markus Peck-Radosavljevic (143105), Albert Stättermayer (829817), Berit Anna Payer (143074)   +12 more
core   +1 more source

Trajectories of medication for opioid use disorder and their impact on HIV testing among people who inject drugs in India: A longitudinal assessment of clinic‐based data

Addiction, Volume 120, Issue 4, Page 745-755, April 2025.
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall, Lakshmi Ganapathi, Mihili P. Gunaratne, Aylur K. Srikrishnan, Conjeevaram K. Vasudevan, Santhanam Anand, Sunil S. Solomon, Shruti H. Mehta, Gregory M. Lucas   +8 more
wiley   +1 more source

State transition model of early hepatitis C natural history.

, 2019
ALD: Advanced liver disease. SVR: Sustained virologic response.
William W. L. Wong (4789398), Abdullah Hamadeh (221909), Zeny Feng (3834667), Murray Krahn (250684)   +3 more
core   +1 more source

Nonzero Risk of Hepatocellular Carcinoma Even after Sustained Virological Response

Gut and Liver, 2016
Approximately 130 to 150 million people are chronically infected with hepatitis C virus (HCV) in the world. HCV infection is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma (HCC). The existence of hepatitis C— originally identifiable only as a type of non-A, non-B hepatitis— was suggested in the 1970s and proven in 1989.
openaire   +4 more sources

Serum Agalactosyl IgG Predicts Hepatocellular Carcinoma and All‐Cause Mortality After SVR in Advanced Chronic Hepatitis C

Hepatology Research, EarlyView.
ABSTRACT Background and Aims Patients with chronic hepatitis C and advanced fibrosis remain at substantial risk of hepatocellular carcinoma (HCC) and non‐liver–related death even after sustained virological response (SVR) to direct‐acting antivirals (DAA).
Daisuke Sakon, Jumpei Kondo, Yuki Tahata, Hayato Hikita, Maki Iwaisako, Muya Matsumoto, Asuka Ogata, Shinji Takamatsu, Yasutoshi Nozaki, Naruyasu Kakita, Hisashi Ishida, Fumihiko Nakanishi, Yuichi Yoshida, Masanori Nakahara, Kazuho Imanaka, Mitsuru Sakakibara, Takayuki Yakushijin, Tetsuo Takehara, Takahiro Kodama, Eiji Miyoshi   +19 more
wiley   +1 more source

Clinical Outcomes of Gradual Corticosteroid Tapering for Immune Checkpoint Inhibitor‐Induced Liver Injury

Hepatology Research, EarlyView.
Patients with severe ICI‐induced liver injury are commonly treated with corticosteroids, but the optimal tapering strategy remains uncertain. In this study, a gradual corticosteroid tapering strategy based partly on Japanese clinical practice for autoimmune hepatitis was associated with a low rate of relapse and enabled many patients to safely resume ...
Naoto Soma, Yoshihito Uchida, Kayoko Sugawara, Masamitsu Nakao, Nobuaki Nakayama, Yukinori Imai, Suguru Mizuno, Satoshi Mochida   +7 more
wiley   +1 more source

Rapid Intrasegmental Progression After Percutaneous Radiofrequency Ablation for Hepatocellular Carcinoma: Incidence, Imaging Features, and Clinical Outcomes

Hepatology Research, EarlyView.
ABSTRACT Aim Radiofrequency ablation (RFA) is curative therapy for early‐stage hepatocellular carcinoma (HCC), but a rare subset of patients develop aggressive intrasegmental recurrence shortly after complete ablation. We characterized the incidence, risk factors, and absolute risk.
Takuma Kaneko, Takuma Nakatsuka, Ryosuke Tateishi, Keisuke Mabuchi, Yuki Matsushita, Tomoharu Yamada, Tatsuya Minami, Masaya Sato, Mitsuhiro Fujishiro   +8 more
wiley   +1 more source