Results 161 to 170 of about 296,469 (371)
HMGB1 Assists in Overcoming Cisplatin Resistance in Chemoresistant Human Ovarian Cancer Cells
Molecular Carcinogenesis, EarlyView.ABSTRACT Cisplatin is one of the most effective chemotherapeutic agents used in the treatment of ovarian cancer. However, the frequent development of cisplatin resistance remains a significant limitation, leading to therapeutic failure and poor patient outcomes.
Van Huynh +3 more
wiley +1 more source
A151 OSEPHAGEAL VARICEAL RECURRENCE 4 YEARS BEYOND ENDOSCOPIC BAND LIGATION IN HEPATITIS C PATIENTS WHO ACHIEVED SUSTAINED VIROLOGICAL RESPONSE WITH ORAL DIRECT ACTING ANTIVIRAL THERAPIES [PDF]
, 2023 Mohamed Abdel‐Samiee +2 more
openalex +1 more source
Nano Select, EarlyView.Antibacterial micro/nanorobots (MNRs) represent a breakthrough in antibacterial therapy, making precise delivery of drugs to the infection site. This review systematically summarizes the material composition, actuation, and applications of MNRs in combating biofilms and drug‐resistant infections while emphasizing the existing challenges of ...
Yichao Chen +4 more
wiley +1 more source
Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental CollegeOver the past three decades, the prevalence of hepatitis C virus (HCV) in Pakistan has remained persistently high, with no signs of decline1. Despite collaborative efforts to combat this viral epidemic, the shadow of HCV continues to loom large over our
Fizza khalid
doaj +1 more source
Obesity, EarlyView.Adipose tissue as a potential reservoir for and modifier of SARS‐CoV‐2 infection and its complications. Schematic demonstrating the differences in subcutaneous and visceral adipose tissue and infection capacity of SARS‐CoV‐2 with interplay between macrophages and adipocytes as target cells for viral tropism.
Liam Charles Maher +2 more
wiley +1 more source
Real-world effectiveness of voxilaprevir/velpatasvir/sofosbuvir in patients following DAA failure
JHEP ReportsBackground & Aims: Voxilaprevir/velpatasvir/sofosbuvir (VOX/VEL/SOF) is highly effective for re-treatment of direct-acting antiviral (DAA)-experienced patients with chronic HCV infection.
Christiana Graf +14 more
doaj +1 more source
Portal Hypertension &Cirrhosis, EarlyView.In a retrospective cohort of 236 patients with type 2 diabetes (T2DM), metabolic dysfunction‐associated steatotic liver disease (MASLD) was common and significant fibrosis (liver stiffness measurement [LSM] ≥8 kPa) was frequently observed. Serum chitinase‐3‐like protein 1 (CHI3L1) correlated with LSM (r = 0.48) and remained an independent predictor of ...
Lixia Sun +8 more
wiley +1 more source
Brazilian Journal of Infectious DiseasesInterferon-α based therapy for chronic hepatitis C (CHC) is associated with thyroiditis and thyroid dysfunction (TD). This study investigated whether TD during pegylated interferon-a (PEG-IFN) plus ribavirin treatment favors sustained viral response (SVR)
Sener Barut +3 more
doaj +1 more source
Building capacity in vector‐borne plant virus research: The CONNECTED Network
PLANTS, PEOPLE, PLANET, EarlyView.Plant viruses spread by insects decimate crop yields globally, causing food security challenges in vulnerable areas, including regions of Africa. Interdisciplinary research is needed to protect future crop supplies. CONNECTED, the Community Network for African Vector‐Borne Plant Viruses, increased research capacity in Central, East, West and Southern ...
Nina F. Ockendon‐Powell +8 more
wiley +1 more source
Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux +6 more
wiley +1 more source