Results 81 to 90 of about 12,993 (261)

What happened after the epidemic? Equine influenza surveillance sheds light on sources and seasonal risk in the United Kingdom

Equine Veterinary Journal, EarlyView.
Abstract Background The epidemiology of equine influenza (EI) in the United Kingdom has not been systematically described since the 2019 epidemic. Objectives To summarise UK EI surveillance (2020–2024), quantify outbreak seasonality and assess movement‐related sources. Study Design Retrospective observational analysis of national surveillance and horse
Fleur Whitlock, John Grewar, Richard Newton   +2 more
wiley   +1 more source

Safety and efficacy of direct-acting antivirals for chronic hepatitis C in patients with chronic kidney disease

BMC Nephrology, 2020
Background This is a real-world evidence study that aims to analyze the efficacy, tolerability and safety profile of paritaprevir/ombitasvir/ritonavir and dasabuvir, in patients with renal impairment.
Elena Laura Iliescu, Adriana Mercan-Stanciu, Letitia Toma   +2 more
doaj   +1 more source

Effectiveness and Safety of Direct-Acting Antivirals in the Treatment of Chronic Hepatitis C: A Real-life Study in Northeastern Brazil [PDF]

Revista da Sociedade Brasileira de Medicina Tropical
Background: This study aimed to evaluate the effectiveness and safety of direct-acting antivirals (DAAs) for hepatitis C treatment by measuring sustained virologic response (SVR) and serious adverse events to help design effective interventions for ...
Elodie Bomfim Hyppolito, Alberto Novaes Ramos Jr, Larissa Peixoto Teixeira, Arthur Machado Bezerra, Lucas Arruda Mendes, Taynara Lais Silva, José Milton de Castro Lima, Érico Antonio Gomes de Arruda, Eder Janes Guerra, Maria Macedo Saraiva Tavares, Carlos Eduardo Pereira Lima, Ticiana Mota Esmeraldo, Francisco Sérgio Rangel de Paula Pessoa, Alessandra Maria Montalverne Pierre, Karla Brandão Pereira, Antônio Haroldo Araújo Filho, Lívia Melo Carone Linhares, Anderson Fuentes Ferreira, Roberto da Justa Pires Neto   +18 more
doaj   +1 more source

Impact of sustained virologic response on quality of life in chronic HVC carriers

Annals of Hepatology, 2013
It is known that patients with chronic hepatitis C have a lower health-related quality of life (HRQOL) than the general population and evidence suggests that the hepatitis C virus (HCV) could exert direct neuropathic action on HRQOL. From this perspective, the virus clearance should be accompanied by improvement in HRQOL.
Renato Daltro-Oliveira, Mychelle Morais-de-Jesus, Karine Miranda Pettersen, Raymundo Paraná, Lucas C. Quarantini   +4 more
openaire   +3 more sources

Availability of Cancer Screening Across HIV Treatment Sites in the IeDEA Consortium

International Journal of Cancer, EarlyView.
In recent years, incorporating comprehensive cancer screening strategies into routine HIV care has gained growing attention. This survey of 220 sites providing HIV care across 41 countries shows that cervical cancer screening has increased in availability over time.
Rachael A. Pellegrino, Bryan E. Shepherd, Sanjay Pujari, Valeria Fink, Gad Murenzi, Miriam Nakalembe, Sally B. Coburn, Eliane Rohner, Antoine Jaquet, Caroline Lade, Brenda Crabtree Ramirez, Kathryn Anastos, Aggrey Semeere, Lesley S. Park, Limpho Mokone, Simon Boni, I Ketut Agus Somia, Emilia M. Jalil, Adebola Adedimeji, Omenge Orang'o, Michael J. Silverberg, Kumbirai Pise Quarter, Eugène Messou, Jeremy Ross, Eduardo Gotuzzo, Patricia Lelo, Helen Byakwaga, Oliver Ezechi, Jonathan Euvrard, Fernanda Maruri, Chad J. Achenbach, Jessica L. Castilho, on behalf of International epidemiology Databases to Evaluate AIDS (IeDEA)   +32 more
wiley   +1 more source

Impact of a sustained virological response on the long‐term outcome of hepatitis C [PDF]

Liver International, 2011
AbstractA sustained virological response (SVR), defined as undetectable hepatitis C virus (HCV)‐RNA 24 weeks after withdrawal from therapy (SVR‐24w), is the primary endpoint of antiviral therapy in chronic hepatitis C. There is solid evidence that patients who reach this target will remain virus free during long‐term follow‐up, with a risk of late HCV ...
openaire   +3 more sources

Host‐specific and deterministic microbiome assembly in major coleopteran stored‐grain pests

iMetaOmics, EarlyView.
Dual DNA‐ and RNA‐based sequencing profiled the microbiomes of five major coleopteran stored‐grain pests and their wheat flour substrate. The microbiomes differed significantly among hosts and from flour, yet 11 core bacterial and 9 core fungal taxa were shared across hosts. RNA data revealed host‐specific active microbiota.
Abrar Muhammad, Xiaoqiang Shen, Lichao Chen, Enhui Guo, Huarui Zhang, Xiaoyu Lei, Chao Sun, Jianhua Lv, Yongqi Shao   +8 more
wiley   +1 more source

Pioneering the canine model in microbiota–gut–brain research for social and affective disorders

iMetaOmics, EarlyView.
This commentary highlights the translational potential of canine models in investigating the microbiota–gut–brain (MGB) axis, focusing on their relevance to human social cognition and affective disorders, including major depressive disorder and autism spectrum disorder.
Yun Yu, Qiuhan Wen, Xiaoyang Wang, Mengyu Song, Tifei Yuan, Feilong Deng, Jianmin Chai, Ying Li, Ya‐Ping Zhang   +8 more
wiley   +1 more source

Antiviral defense systems drive persistence of antimicrobial‐resistant bacteria but limit the transfer of antimicrobial resistance genes in anaerobic digestion

iMeta, EarlyView.
Phage–host interactions critically shape environmental antimicrobial resistance (AMR). Using swine manure anaerobic digestion and multi‐omics (metagenomics, meta‐transcriptomics, and Hi‐C), we mapped the phage–bacteria arms race and its impact on AMR dynamics.
Junya Zhang, Tiedong Lu, Qihe Tang, Song‐Can Chen, Daniel Rios Garza, Bin Liu, Yunwei Cui, Yuansong Wei, Hans Hermann Richnow   +8 more
wiley   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source