Results 101 to 110 of about 5,500,616 (251)

Genetic switch to lower nitrogen fertilizer dependency and enhance maize yield

iMetaOmics, EarlyView.
Transcription factor NCR1 regulates nitrate transporter NRT2.3 and controls root‐to‐shoot nitrogen transport. A superior NCR1 haplotype, lost in modern maize breeding, boosts this process. This discovery enables breeding and biotechnology to develop high‐yielding maize varieties that require less nitrogen fertilizer, reducing agricultural costs and ...
Sunil S. Gangurde, Dhliwayo Thanda, Qingguo Du, Liang Li, Jiwang Zhang, Pervez H. Zaidi, Boddupalli Maruthi Prasanna, Xuecai Zhang, Linmao Zhao, Ashish Saxena   +9 more
wiley   +1 more source

Impact of sustained virologic response on quality of life in chronic HVC carriers

Annals of Hepatology, 2013
It is known that patients with chronic hepatitis C have a lower health-related quality of life (HRQOL) than the general population and evidence suggests that the hepatitis C virus (HCV) could exert direct neuropathic action on HRQOL. From this perspective, the virus clearance should be accompanied by improvement in HRQOL.
Renato Daltro-Oliveira, Mychelle Morais-de-Jesus, Karine Miranda Pettersen, Raymundo Paraná, Lucas C. Quarantini   +4 more
openaire   +3 more sources

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Impact of a sustained virological response on the long‐term outcome of hepatitis C [PDF]

Liver International, 2011
AbstractA sustained virological response (SVR), defined as undetectable hepatitis C virus (HCV)‐RNA 24 weeks after withdrawal from therapy (SVR‐24w), is the primary endpoint of antiviral therapy in chronic hepatitis C. There is solid evidence that patients who reach this target will remain virus free during long‐term follow‐up, with a risk of late HCV ...
openaire   +3 more sources

Sustained virologic response to therapy of recurrent hepatitis C after liver transplantation is related to early virologic response and dose adherence [PDF]

, 2007
Sustained virologic response (SVR) after antiviral therapy for recurrent hepatitis C virus (HCV) infection in liver transplant (LT) recipients is consistently lower than that achieved in non-LT patients.
Lok, Anna Suk-Fong, Greenson, Joel K., Conjeevaram, Hari S., Grace L. Su, Marrero, Jorge A., Robert J. Fontana, Frederick Askari, Askari, Frederick K., Patricia Sullivan, Fontana, Robert John, Hari Conjeevaram, Pratima Sharma, Su, Grace L., Joel K. Greenson, Anna S. Lok, Sharma, Pratima, Sullivan, Patricia, Jorge A. Marrero   +17 more
core   +1 more source

Interleukin‐37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence‐Free Survival in Hepatocellular Carcinoma Patients

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Hepatocellular carcinoma (HCC) remains a major cause of cancer‐related mortality worldwide, and postoperative recurrence continues to limit long‐term survival. Liver‐resident natural killer (NK) cells are key effectors of antitumor immunity in the hepatic microenvironment. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine, has
Yuki Imaoka, Masahiro Ohira, Yuka Tanaka, Toshihiro Nakayama, Miho Akabane, Shinichiro Yokota, Sheri M. Krams, Olivia M. Martinez, Carlos O. Esquivel, Kazunari Sasaki, Hideki Ohdan   +10 more
wiley   +1 more source

Genotype frequencies and sustained virologic response (SVR) rates of IFNL3 rs12979860 and rs8099917 SNPs in the evaluation and replication cohort.

, 2013
Genotype frequencies and sustained virologic response (SVR) rates of IFNL3 rs12979860 and rs8099917 SNPs in the evaluation and replication cohort.
Simone Susser (48294), Annika Brodzinski (477753), Balazs Fülöp (477754), Thomas Berg (186372), Jacob George (205614), Stephan Böhm (334611), Christoph Sarrazin (48298), Tobias Müller (163591), Janett Fischer (477751), Eckart Schott (320945), Graeme Stewart (208243), Heiko Witt (161481), Pascal Migaud (477752), Florian van Bömmel (477755)   +13 more
core   +1 more source

Absence of progressive liver disease after treatment in children with chronic hepatitis C: A nationwide registry study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives In adults with chronic hepatitis C (CHC) and advanced fibrosis, hepatocellular carcinoma (HCC) surveillance is recommended after achieving a sustained virologic response (SVR). However, post‐SVR surveillance strategies for children remain unclear. The aim of this study was to assess the durability of SVR and determine an appropriate
Hitoshi Tajiri, Mitsuyoshi Suzuki, Yuri Etani, Yoshinori Ito, Koichi Ito, Tomoya Fukuoka, Tatsuki Mizuochi   +6 more
wiley   +1 more source

Effectiveness and Safety of Direct-Acting Antivirals in the Treatment of Chronic Hepatitis C: A Real-life Study in Northeastern Brazil [PDF]

Revista da Sociedade Brasileira de Medicina Tropical
Background: This study aimed to evaluate the effectiveness and safety of direct-acting antivirals (DAAs) for hepatitis C treatment by measuring sustained virologic response (SVR) and serious adverse events to help design effective interventions for ...
Elodie Bomfim Hyppolito, Alberto Novaes Ramos Jr, Larissa Peixoto Teixeira, Arthur Machado Bezerra, Lucas Arruda Mendes, Taynara Lais Silva, José Milton de Castro Lima, Érico Antonio Gomes de Arruda, Eder Janes Guerra, Maria Macedo Saraiva Tavares, Carlos Eduardo Pereira Lima, Ticiana Mota Esmeraldo, Francisco Sérgio Rangel de Paula Pessoa, Alessandra Maria Montalverne Pierre, Karla Brandão Pereira, Antônio Haroldo Araújo Filho, Lívia Melo Carone Linhares, Anderson Fuentes Ferreira, Roberto da Justa Pires Neto   +18 more
doaj   +1 more source

Response to antiretroviral therapy after a single, peripartum dose of nevirapine. [PDF]

, 2007
BACKGROUND: A single dose of nevirapine during labor reduces perinatal transmission of human immunodeficiency virus type 1 (HIV-1) but often leads to viral nevirapine resistance mutations in mothers and infants.
van Widenfelt, Erik, Smeaton, Laura M, Chand, Fatima, Lagakos, Stephen, Shapiro, Roger L, Stevens, Lisa, Novitsky, Vladimir, Wester, Carolyn, Arimi, Peter, Ndase, Patrick, Makhema, Joseph, Asmelash, Aida, Mazhani, Loeto, Lockman, Shahin, Thior, Ibou, Moffat, Claire, Essex, Max   +16 more
core   +1 more source