Results 111 to 120 of about 5,883,314 (302)

Suspected fibrosing cholestatic hepatitis in an immunocompetent child with hepatitis C: Case report

JPGN Reports, EarlyView.
Abstract A 12‐year‐old boy presented to our center with elevated aminotransferases, jaundice, right upper quadrant tenderness, and hepatomegaly. Evaluation revealed a highly elevated blood hepatitis C virus (HCV) ribonucleic acid (RNA) level, and liver biopsy showed canalicular and intrahepatic cholestasis, feathery degeneration of hepatocytes, and ...
Sara Bohon, Regino Gonzalez‐Peralta, Robert J. Fontana, Richard Cordle, Robin LeGallo, Frank DiPaola   +5 more
wiley   +1 more source

Effectiveness and Safety of Direct-Acting Antivirals in the Treatment of Chronic Hepatitis C: A Real-life Study in Northeastern Brazil [PDF]

Revista da Sociedade Brasileira de Medicina Tropical
Background: This study aimed to evaluate the effectiveness and safety of direct-acting antivirals (DAAs) for hepatitis C treatment by measuring sustained virologic response (SVR) and serious adverse events to help design effective interventions for ...
Elodie Bomfim Hyppolito, Alberto Novaes Ramos Jr, Larissa Peixoto Teixeira, Arthur Machado Bezerra, Lucas Arruda Mendes, Taynara Lais Silva, José Milton de Castro Lima, Érico Antonio Gomes de Arruda, Eder Janes Guerra, Maria Macedo Saraiva Tavares, Carlos Eduardo Pereira Lima, Ticiana Mota Esmeraldo, Francisco Sérgio Rangel de Paula Pessoa, Alessandra Maria Montalverne Pierre, Karla Brandão Pereira, Antônio Haroldo Araújo Filho, Lívia Melo Carone Linhares, Anderson Fuentes Ferreira, Roberto da Justa Pires Neto   +18 more
doaj   +1 more source

Long‐term seroepidemiology of European brown hare syndrome in European and Italian hares in Tuscany (Italy)

The Journal of Wildlife Management, EarlyView.
We investigated the presence of European Brown Hare Syndrome (EBHS) in wild hare populations in the province of Grosseto (Italy) over a 16‐year period. The results showed that EBHS is widespread, with about two‐thirds of hares showing evidence of past infection. European hares were more frequently exposed than the rarer Italian hare.
Maria Chiara Fabbri, Mattia Ricci, Patrizia Cavadini, Lorenzo Capucci, Martina Benedetti, Andrea Lombardo, Ziad Mezher, Massimo Machetti, Maria Paola Ponzetta, Francesco Mariottini, Fabio Rossi, Giuseppina Brochelerel, Antonio Lavazza, Giorgia Romeo   +13 more
wiley   +1 more source

Diagnostic Accuracy of Serum‐Based Fibrosis Scores for Clinically Significant Liver Fibrosis in an East Asian Cohort

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Serum‐based fibrosis scores are widely used for noninvasive risk stratification in chronic liver disease; however, direct comparisons across liver disease etiologies remain limited, particularly in Asian populations with a high prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection.
Sheng‐Feng Lin, Chun‐Chao Chang
wiley   +1 more source

Supplementary table -Supplemental material for Long-term changes in liver elasticity in hepatitis C virus-infected patients with sustained virologic response after treatment with direct-acting antivirals

, 2018
Supplemental material, Supplementary table for Long-term changes in liver elasticity in hepatitis C virus-infected patients with sustained virologic response after treatment with direct-acting antivirals by Veronika Pietsch, Katja Deterding, Dina Attia ...
Michael Gebel (5499044), Dina Attia (5499047), Heiner Wedemeyer (32361), Markus Cornberg (32357), Michael Peter Manns (220587), Veronika Pietsch (5499050), Benjamin Heidrich (345028), Kristina Imeen Ringe (716653), Katja Deterding (4967791), Andrej Potthoff (5499041)   +9 more
core   +1 more source

Treatment of Congenital Cytomegalovirus Beyond the Neonatal Period: A Single‐Arm Meta‐Analysis

The Laryngoscope, EarlyView.
This systematic review and single‐arm meta‐analysis evaluated hearing outcomes following antiviral therapy initiated after the neonatal period in children with congenital cytomegalovirus infection. Across eight studies including 192 patients, post‐neonatal treatment was associated with meaningful hearing improvement and low rates of hearing ...
Thamiris D. D. Cabral, Marcela Mafra, Jaime Plane, Matheus Sewastjanow‐Silva, Isadora Martins Nascimento, Asitha D. L. Jayawardena, Abby Meyer, Andrew Redmann, Luke Jakubowski   +8 more
wiley   +1 more source

Supplementary Tables -Supplemental material for Short-term histological evaluations after achieving a sustained virologic response to direct-acting antiviral treatment for chronic hepatitis C

, 2018
Supplemental material, Supplementary Tables for Short-term histological evaluations after achieving a sustained virologic response to direct-acting antiviral treatment for chronic hepatitis C by Masaru Enomoto, Yoshihiro Ikura, Akihiro Tamori, Ritsuzo ...
Yoshiki Murakami (130307), Etsushi Kawamura (4956046), Ritsuzo Kozuka (4956061), Yoshihiro Ikura (5542457), Hideki Fujii (425232), Norifumi Kawada (425245), Hiroyuki Motoyama (4956052), Masaru Enomoto (585577), Akihiro Tamori (156590), Sawako Uchida-Kobayashi (585580), Hiroyasu Morikawa (799295), Atsushi Hagihara (4956049)   +11 more
core   +1 more source

SHP2 in Cancer: From Tumor Biology to Therapeutic Targeting

Medicinal Research Reviews, EarlyView.
ABSTRACT SHP2 is a tyrosine phosphatase that mediates intracellular signaling downstream of transmembrane receptors regulated by a pair of src homology 2 (SH2) domains. Its overexpression and mutation are pivotal in driving tumor progression by influencing various cancer's fundamental characteristics, such as metastasis, DNA repair, angiogenesis ...
Maryam Jama, Michael Overduin, Khaled H. Barakat   +2 more
wiley   +1 more source

Supplementary Figures -Supplemental material for Short-term histological evaluations after achieving a sustained virologic response to direct-acting antiviral treatment for chronic hepatitis C

, 2018
Supplemental material, Supplementary Figures for Short-term histological evaluations after achieving a sustained virologic response to direct-acting antiviral treatment for chronic hepatitis C by Masaru Enomoto, Yoshihiro Ikura, Akihiro Tamori, Ritsuzo ...
Yoshiki Murakami (130307), Etsushi Kawamura (4956046), Ritsuzo Kozuka (4956061), Yoshihiro Ikura (5542457), Hideki Fujii (425232), Norifumi Kawada (425245), Hiroyuki Motoyama (4956052), Masaru Enomoto (585577), Akihiro Tamori (156590), Sawako Uchida-Kobayashi (585580), Hiroyasu Morikawa (799295), Atsushi Hagihara (4956049)   +11 more
core   +1 more source

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

PROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez, Melanie Dos Santos, Mikaël Attia, Killian De Geest, Ibrahim Hamid, Rodrigue Tesse, Ilham Fdillate, Marc Boschmans, Steven Van Borm, Mieke Steensels, Benedicte Lambrecht, Lionel Tafforeau, Caroline Demeret, Cyril Barbezange   +13 more
wiley   +1 more source