Results 111 to 120 of about 5,500,616 (251)

Impact of Cardiometabolic Risk Factors and Steatotic Liver Disease on Liver‐Related Outcomes in Patients With Chronic Hepatitis C After Curative Antiviral Therapy

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Patients with chronic hepatitis C (CHC) frequently present with steatotic liver disease (SLD) and cardiometabolic risk factors (CMRFs). This study aimed to evaluate the impact of SLD and CMRFs on liver‐related outcomes (LROs) in CHC patients after HCV eradication.
Chung‐Feng Huang   +15 more
wiley   +1 more source

Sustained virologic response derived by genotype, cirrhosis status, HCV prior treatment, and treatment regimen, in intention-to-treat and modified intention-to-treat assessment (n = 527).

open access: yes, 2018
Sustained virologic response derived by genotype, cirrhosis status, HCV prior treatment, and treatment regimen, in intention-to-treat and modified intention-to-treat assessment (n = 527).
Leticia Pisoni Zanaga (5497430)   +8 more
core   +1 more source

Treatment of Congenital Cytomegalovirus Beyond the Neonatal Period: A Single‐Arm Meta‐Analysis

open access: yesThe Laryngoscope, EarlyView.
This systematic review and single‐arm meta‐analysis evaluated hearing outcomes following antiviral therapy initiated after the neonatal period in children with congenital cytomegalovirus infection. Across eight studies including 192 patients, post‐neonatal treatment was associated with meaningful hearing improvement and low rates of hearing ...
Thamiris D. D. Cabral   +8 more
wiley   +1 more source

The FOXQ1/SSBP2 Regulatory Axis Drives Malignant Progression of Melanoma

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Melanoma is a highly aggressive skin cancer with poor prognosis, often linked to excessive UV exposure. Despite advancements in immunotherapy and targeted treatments, melanoma's invasiveness and metastatic potential remain significant challenges.
Xiaoyu Zhang   +4 more
wiley   +1 more source

The sustained virologic response (SVR) 12 rate in the patients with co-existing NS5A and NS5B RASs.

open access: yes, 2018
The interferon (IFN) free-naïve patients with coexisting resistance-associated substitutions (RASs) of Q24, L28, and/or R30, L31, or Y93 and NS5B A218 and/or C316 had a significantly lower sustained virologic response (SVR) 12 rate in comparison to the ...
Takeshi Kure (5328974)   +16 more
core   +1 more source

Chemopreventive Effect of Bitter Melon (Momordica charantia) Juice on Pancreatic Carcinogenesis in LSL‐KrasG12D/+; p48Cre/+ Mice

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Herein, using the LSL‐KrasG12D/+; p48Cre/+ transgenic mouse model [that recapitulates the full spectrum of human disease, progressing from early pancreatic intraepithelial neoplasia lesions to invasive pancreatic ductal adenocarcinoma (PDAC)], we determined the chemopreventive effect of long‐term (chronic) administration of Bitter Melon Juice (
Lakshmi Sai Pratyusha Bugata   +7 more
wiley   +1 more source

Patient characteristics at hepatitis C virus (HCV) treatment start, treatment duration and sustained virologic response (SVR) according to HCV genotype group.

open access: yes, 2015
Abbreviations: ART, antiretroviral therapy; HCV, hepatitis C virus; IDU, intravenous drug user; IQR, interquartile range; MSM, men who have sex with men; SVR, sustained viral response.Patient characteristics at hepatitis C virus (HCV) treatment start ...
Marcel Stöckle (776301)   +12 more
core   +1 more source

Post‐Mortem Nasal Swab Testing to Reveal Hidden Respiratory Pathogens: Unlocking Public Health Insights in Bangladesh

open access: yesMedicine Advances, EarlyView.
Respiratory deaths in Bangladesh are frequently assigned non‐specific causes because of limited diagnostic information. Through stakeholder consultations, key informant interviews, microbiologist consultations, and literature review, 11 priority respiratory pathogens were identified for potential detection using post‐mortem nasal swab testing and ...
Ridwana Maher Manna   +1 more
wiley   +1 more source

Ranavirus risk depends on host community characteristics more than the presence of Batrachochytrium dendrobatidis

open access: yesOikos, EarlyView.
Novel parasite introductions are threatening wildlife communities globally. The degree of threat depends on the ecological context, namely host community characteristics and the presence of other parasites. How these two factors interact to shape the outcomes of parasite introductions is not known. We experimentally investigated how infection following
David R. Daversa   +5 more
wiley   +1 more source

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez   +13 more
wiley   +1 more source

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