Results 101 to 110 of about 479 (110)
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Interactions of sutezolid and its active metabolite with human transporters
Drug Metabolism and PharmacokineticsNathalie Rioux
exaly +2 more sources
Sutezolid. Oxazolidinone antibacterial, treatment of tuberculosis
Drugs of the Future, 2013null Lanoix, J.-P., null Nuermberger, E.
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Sutezolid: A promising next generation tuberculosis agent
World Journal of Biology Pharmacy and Health SciencesSutezolid (PNU-100480) is an advanced oxazolidinone antibiotic that shows strong effectiveness against Mycobacterium tuberculosis, including those tough multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains. It works by blocking bacterial protein synthesis, specifically by attaching to the 23S rRNA of the 50S ribosomal subunit, which ...
Kiran, Garlapati Usha +5 more
exaly +2 more sources
Antimicrobial agents and chemotherapy, 2015
Sutezolid (PNU-100480 [U-480]) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis. An active sulfoxide metabolite (PNU-101603 [U-603]), which reaches concentrations in plasma several times those of the parent, has been reported to drive the killing of extracellular Mycobacterium tuberculosis by sutezolid in hollow-fiber
Zhu, Tong +3 more
openaire +2 more sources
Sutezolid (PNU-100480 [U-480]) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis. An active sulfoxide metabolite (PNU-101603 [U-603]), which reaches concentrations in plasma several times those of the parent, has been reported to drive the killing of extracellular Mycobacterium tuberculosis by sutezolid in hollow-fiber
Zhu, Tong +3 more
openaire +2 more sources
PanACEA Sutezolid Dose-finding and Combination Evaluation
Case Medical Research, 2019openaire +1 more source
Sutezolid & Delpazolid - Ein wichtiger Fortschritt bei multiresistenter Tuberkulose
Österreichische Apothekerzeitungopenaire +1 more source