Results 121 to 128 of about 704 (128)

Enantioselective recognition of sutezolid by cyclodextrin modified non-aqueous capillary electrophoresis and explanation of complex formation by means of infrared spectroscopy, NMR and molecular modelling

Journal of Pharmaceutical and Biomedical Analysis, 2019
A method for the enantioseparation of sutezolid, the next analogue after linezolid and tedizolid, belonging to the truly new class of antibacterial agents, the oxazolidinones, was developed based on non-aqueous capillary electrophoresis (NACE), using a single isomer of cyclodextrins as a chiral pseudophase.
Katarzyna Michalska, Wojciech Bocian, ElŻbieta Bednarek   +2 more
exaly   +4 more sources

Interactions of sutezolid and its active metabolite with human transporters

Drug Metabolism and Pharmacokinetics
Upendra A. Argikar, Nathalie Rioux, Monicah A. Otieno   +2 more
exaly   +3 more sources

PanACEA Sutezolid Dose-finding and Combination Evaluation

Case Medical Research, 2019
Kernel Networks Inc.
openalex   +2 more sources

Synergistic activity of fosfomycin combined with old and new oxazolidinones (linezolid, contezolid, delpazolid, and sutezolid) against bloodstream isolates of vancomycin-resistant Enterococcus faecium

European Journal of Clinical Microbiology and Infectious Diseases
Stefano Di Bella
exaly   +2 more sources

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Population pharmacokinetic/pharmacodynamic analysis of the bactericidal activities of sutezolid (PNU-100480) and its major metabolite against intracellular Mycobacterium tuberculosis in ex vivo whole-blood cultures of patients with pulmonary tuberculosis.

Antimicrobial agents and chemotherapy, 2015
Sutezolid (PNU-100480 [U-480]) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis. An active sulfoxide metabolite (PNU-101603 [U-603]), which reaches concentrations in plasma several times those of the parent, has been reported to drive the killing of extracellular Mycobacterium tuberculosis by sutezolid in hollow-fiber
Zhu, Tong, Friedrich, Sven O., Diacon, Andreas, Wallis, Robert S.   +3 more
openaire   +2 more sources

Sutezolid, a Potential New Weapon Against TB

, 2012
Helmut Albrecht
openalex   +1 more source

Nonaqueous capillary electrophoretic separation of sutezolid enantiomers using charge single isomer derivatives of cyclodextrins

2017
Michalska, Katarzyna, Gruba, Ewa, Pałys, Barbara, Judyta Cielecka-Piontek   +3 more
openaire   +1 more source

PanACEA Sutezolid Dose-finding and Combination Evaluation

Case Medical Research
exaly