Results 181 to 190 of about 101,772 (313)

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

Advanced Science, EarlyView.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak, Juliane Tschuck, Stefanie A. I. Weiß, Daniel Kaemena, Karolin Klimm, Ana Galhoz, Larissa Ringelstetter, Myles Fennell, Juliane Merl‐Pham, Anna Artati, Stefanie Strasser, Ralph Garippa, Michael Witting, Hans Zischka, Joel A. Schick, Stefanie M. Hauck, Michael P. Menden, Michelle Vincendeau, Brent R. Stockwell, Kamyar Hadian   +19 more
wiley   +1 more source

Family planning, sexual activity and contraception in hereditary hemorrhagic telangiectasia: a European survey study. [PDF]

Orphanet J Rare Dis
Hessels J, Post MC, Boerman S, Droege F, Dupuis O, ePAG, Geisthoff UW, Haahr PD, Kjeldsen AD, Mager JJ, Dupuis-Girod S, Buscarini E.   +11 more
europepmc   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Heja Sverige!

Lähikuva – audiovisuaalisen kulttuurin tieteellinen julkaisu, 2009
openaire   +2 more sources

Experiences of sleep problems, subsequent daytime consequences, and self-care activities used to improve sleep among patients with restless legs syndrome: a qualitative content analysis. [PDF]

J Res Nurs
Odzakovic E, Ingelsbo Petersson A, Lindholm Ericsson E, Öberg S, Jakobsson M, Björk M, Knutsson S, Fridlund B, Jonasson LL, Ulander M, Lind J, Broström A.   +11 more
europepmc   +1 more source

Grovt upphovsrättsbrott och grovt varumärkesbrott betänkande av Utredningen om vissa allvarliga immaterialrättsintrång

, 2018
Sverige
core  

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

Advanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan, Nathaly A. Chicaiza‐Cabezas, Florian Kleefeldt, Philipp Wörsdörfer, Jürgen Groll, Süleyman Ergün   +5 more
wiley   +1 more source

Sveriges miljömål

, 2011
Sveriges miljömål är viktiga för vår framtid. Riksdagen har antagit 16 mål för miljökvaliteten i Sverige. Målen beskriver den kvalitet och det tillstånd i miljön som är hållbara på lång sikt. Generationsmålet är det övergripande målet för miljöpolitiken. Det anger riktningen och bör vara vägledande för miljöarbetet på alla nivåer i samhället.
openaire   +1 more source

Red meat intake during pregnancy and childhood and risk of type 1 diabetes: findings from the ABIS birth cohort. [PDF]

Diabetologia
Lampousi AM, Zeng J, Löfvenborg JE, Carlsson S, Ludvigsson J.   +4 more
europepmc   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source