Results 211 to 220 of about 216,233 (295)

Self-reported pelvic floor dysfunction 12 months after an obstetric anal sphincter injury in relation to maternal body mass index. [PDF]

Acta Obstet Gynecol Scand
Hjertberg L, Uustal E, Blomberg M, Pihl S.   +3 more
europepmc   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

Effect of engineered mesoporous silica particles with tailored pore size on glycaemic control in individuals with prediabetes or type 2 diabetes: a randomised, double-blind, placebo-controlled SHINE trial. [PDF]

EClinicalMedicine
Baek J, Ioannidou A, Borg ML, Robert-Nicoud G, Pietiläinen KH, Rössner S, Johnston EV, Bengtsson T.   +7 more
europepmc   +1 more source

40 år av ockupation - nu är det nog! [PDF]

, 2007
Palestinagrupperna i Sverige
core  

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source

Family planning, sexual activity and contraception in hereditary hemorrhagic telangiectasia: a European survey study. [PDF]

Orphanet J Rare Dis
Hessels J, Post MC, Boerman S, Droege F, Dupuis O, ePAG, Geisthoff UW, Haahr PD, Kjeldsen AD, Mager JJ, Dupuis-Girod S, Buscarini E.   +11 more
europepmc   +1 more source

Sveriges Genusforskarförbund

Tidskrift för genusvetenskap, 2015
openaire   +1 more source

Arrayed Magnetic Accelerator Synergistically Enhances Orthodontic Tooth Movement via Microtubule Assembly‐Mediated Periodontal Remodeling

Advanced Science, EarlyView.
Mechanical orthodontic treatment for malocclusion is limited by slow remodeling and risks due to poor biomechanical sensing. This study shows that static magnetic fields (SMFs) enhance mechanical sensation in periodontal ligament cells, promoting inflammation and osteoclast activity.
Yiling Lou, Jiwei Sun, Peng Chen, Caihong Mao, Junyuan Zhang, Haoqi Lei, Xiaoqing Han, Yaxuan Zhang, Yuheng Jiang, Yulin Jia, Bin Su, Lili Chen   +11 more
wiley   +1 more source

Thromboxane signalling links immune activation to enhanced glucose uptake in skeletal muscle. [PDF]

Diabetologia
Abdelmoez AM, Jollet M, Yu X, Rizo-Roca D, Marica AA, Ortiz de Zevallos J, Dollet L, Borg ML, Björnholm M, Checa A, Olsson T, Otten J, Zierath JR, Krook A, Schwartz TW, Chibalin AV, Pillon NJ.   +16 more
europepmc   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source