Results 231 to 240 of about 216,233 (295)

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren   +11 more
wiley   +1 more source

Interleukin‐1α Mediates Pancreatic Fibroblast Activation, Regulates Immune Cell Recruitment and Fibrosis in Acute and Chronic Pancreatitis

open access: yesAdvanced Science, EarlyView.
During pancreatitis, IL‐1α is released from necrotic acinar cells. In response to IL‐1α, pancreatic fibroblasts release chemokines and cytokines that regulate the recruitment of immune cells to the damaged organ. Furthermore, IL‐1α primes fibroblasts, resulting in increased tissue fibrosis during chronic pancreatitis.
Hala Mazloum   +13 more
wiley   +1 more source

Prognostic performance of thymidine kinase 1 activity in patients with hormone receptor-positive and HER2-negative metastatic breast cancer treated with CDK4/6 and aromatase inhibitors. [PDF]

open access: yesBreast Cancer Res Treat
Brown NL   +12 more
europepmc   +1 more source

High Upper Critical Field and Type II Superconductivity in Epitaxial Cubic W2N Thin Films

open access: yesAdvanced Science, EarlyView.
Superconducting thin films of stoichiometric W2N demonstrate a high upper critical field (Hc2) of ∼ 8.5 T, uncommon among binary transition metal nitrides. This robust superconducting response under high magnetic fields highlights the technological relevance of W2N for superconducting applications, e.g., integrated quantum and cryogenic electronics ...
Aditya Singh   +7 more
wiley   +1 more source

Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population. [PDF]

open access: yesHeart
Kylhammar D   +11 more
europepmc   +1 more source

Variations in antibiotic use in late preterm and term newborns from 2012 to 2020: a nationwide population-based observational study. [PDF]

open access: yesArch Dis Child Fetal Neonatal Ed
Gyllensvärd J   +7 more
europepmc   +1 more source

LOs program för utbildningspolitiken sammanfattning

open access: yes, 1977
Landsorganisationen i Sverige
core  

The Economic Burden of Alopecia Areata: Evidence from a Survey in Norway and Sweden. [PDF]

open access: yesActa Derm Venereol
Löfvendahl S   +5 more
europepmc   +1 more source

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