Results 41 to 50 of about 3,235 (254)

Sweetness Preferences and Caries detection in Schoolchildren of Hamedan/Iran

open access: yesFrontiers in Dentistry, 2008
Objective: Despite the strong relationship between sugars, mutans streptococcilevels and caries, relatively, little research has been carried out on one of the factors that may influ-ence sugar intake; namely sweet preference.
F. Mojarrad   +2 more
doaj  

Consumption of non-nutritive sweeteners by pre-schoolers of the food and environment Chilean cohort (FECHIC) before the implementation of the Chilean food labelling and advertising law

open access: yesNutrition Journal, 2020
Background Consumption of non-nutritive sweeteners (NNS) is becoming increasingly more frequent, particularly in the context of obesity prevention policies.
Carolina Venegas Hargous   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

EDULCORANTES NATURALES UTILIZADOS EN LA ELABORACIÓN DE CHOCOLATES

open access: yesBiotecnología en el Sector Agropecuario y Agroindustrial, 2017
The demand of confectionery products and their massive consumption, leads to the agri-food industry include in its transformation processes inputs that improve the nutritional quality of the final products.
ESTEBAN PALACIO VÁSQUEZ   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

GELS FOR ORAL ADMINISTRATION. PART 2. EXCIPIENTS (REVIEW)

open access: yesРазработка и регистрация лекарственных средств, 2019
The characteristics of the excipients as components of gels for oral administration have been considered in the article. The properties of gelatinizing, sweetening and preservation agents have been described.
E. Y. Zagorulko, A. A. Teslev
doaj  

Design, formulation and evaluation of nicotine chewing gum

open access: yesAdvanced Biomedical Research, 2012
Background: Nicotine replacement therapy (NRT) can help smokers to quit smoking. Nicotine chewing gum has attracted the attention from pharmaceutical industries to offer it to consumers as an easily accessible NRT product.
Abolfazl Aslani, Sahar Rafiei
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Gut Microbiota—A New Concern on Health Regulation(肠道菌群:膳食与健康研究的新视角) [PDF]

open access: yesShipin kexue jishu xuebao, 2015
With the development of “Human Microbiome Project” and “Metagenomics of the Human Intestinal Tract”, great attention has been paid on human gut microbiota. With the increasing knowledge of the composition and function of gut microbiota, we found that gut
CHEN Wei(陈 卫)
doaj   +1 more source

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