Results 61 to 70 of about 10,169 (345)

Design, formulation and evaluation of nicotine chewing gum

open access: yesAdvanced Biomedical Research, 2012
Background: Nicotine replacement therapy (NRT) can help smokers to quit smoking. Nicotine chewing gum has attracted the attention from pharmaceutical industries to offer it to consumers as an easily accessible NRT product.
Abolfazl Aslani, Sahar Rafiei
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Towards general spatial intelligence [PDF]

open access: yes, 2008
The goal of General Spatial Intelligence is to present a unified theory to support the various aspects of spatial experience, whether physical or cognitive.
Domingue, John, Tanasescu, Vlad
core   +1 more source

Analytic Metaphysics versus Naturalized Metaphysics: The Relevance of Applied Ontology [PDF]

open access: yes, 2018
The relevance of analytic metaphysics has come under criticism: Ladyman & Ross, for instance, have suggested do discontinue the field. French & McKenzie have argued in defense of analytic metaphysics that it develops tools that could turn out to be ...
A Barton   +38 more
core   +5 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

GELS FOR ORAL ADMINISTRATION. PART 2. EXCIPIENTS (REVIEW)

open access: yesРазработка и регистрация лекарственных средств, 2019
The characteristics of the excipients as components of gels for oral administration have been considered in the article. The properties of gelatinizing, sweetening and preservation agents have been described.
E. Y. Zagorulko, A. A. Teslev
doaj  

Storage of organically produced crops (OF0127T) [PDF]

open access: yes, 1997
This is the final report of Defra Project OF0127T. The main objective of this review was to establish best storage practice for field vegetables, potatoes, cereals and top fruit. A literature review was carried out and information was also gathered from
Bevan, J. R., Firth, C., Neicho, M.
core  

Non-human tools for the evaluation of bitter taste in the design and development of medicines: a systematic review [PDF]

open access: yes, 2016
Taste evaluation is a crucial factor for determining acceptance of medicines by patients. The human taste panel test is the main method used to establish the overall palatability and acceptability of a drug product to a patient towards the end of ...
Ernest, T   +3 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Gender differences in perceived food healthiness and food avoidance in a Swedish population-based survey: a cross sectional study

open access: yesNutrition Journal, 2020
Background The aim of this work was to study potential gender differences in perceived food healthiness and food avoidance in a population-representative sample of the Swedish adult population. Methods A questionnaire regarding diet and health was posted
Linnea Bärebring   +3 more
doaj   +1 more source

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