Results 81 to 90 of about 3,202,342 (331)
Italian Journal of Agronomy, 2008 Stevia rebaudiana Bertoni is a herbaceous perennial plant originating in the north-east of Paraguay. Its leaves contain low-calorie sweetening agents that can be used as a natural alternative to artificial sweeteners.
Riccardo d’Andria +5 more
doaj +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Revista Brasileira de Ginecologia e Obstetrícia, 2007 Os adoçantes são freqüentemente utilizados por mulheres em idade reprodutiva. Esta é uma revisão narrativa da literatura a respeito dos adoçantes atualmente comercializados no mercado brasileiro.
Maria Regina Torloni +6 more
doaj +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Cooperative Heterogeneous Deep Reinforcement Learning [PDF]
arXiv, 2020 Numerous deep reinforcement learning agents have been proposed, and each of them has its strengths and flaws. In this work, we present a Cooperative Heterogeneous Deep Reinforcement Learning (CHDRL) framework that can learn a policy by integrating the advantages of heterogeneous agents.
arxiv
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Revue de Primatologie, 2015 Over the past few decades there has been a growing interest into social learning in animals. The importance of social influence on food choice has been demonstrated across a number of species including humans.
Gladez Shorland +2 more
doaj +1 more source
Sucralose Interaction with Protein Structures [PDF]
arXiv, 2017 Sucralose is a commonly employed artificial sweetener that appears to destabilize protein native structures. This is in direct contrast to the bio-preservative nature of its natural counterpart, sucrose, which enhances the stability of biomolecules against environmental stress.
arxiv
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
The reliability of a nutritional meta-analysis study [PDF]
arXiv, 2017 Background: Many researchers have studied the relationship between diet and health. There are papers showing an association between the consumption of sugar-sweetened beverages and Type 2 diabetes. Many meta-analyses use individual studies that do not adjust for multiple testing or multiple modeling and thus provide biased estimates of effect.
arxiv