Results 81 to 90 of about 2,971,207 (141)

Coronavirus non-structural protein 1 is a major pathogenicity factor : implications for the rational design of coronavirus vaccines [PDF]

, 2007
Zust, Roland Cervantes-Barragan, Luisa Kuri, Thomas Blakqori, Gjon Weber, Friedemann Ludewig, Burkhard Thiel, Volker 5 R21 AI062246/AI/United States NIAID Research Support, N.I.H., Extramural Research Support, Non-U.S.
Thiel Volker, Friedemann Weber, Cervantes-Barragan, L., Kuri, Thomas, Roland Züst, Kuri Thomas, Weber, Friedemann, Weber, F., Volker Thiel, Luisa Cervantes-Barragán, Kuri, T., Zust, R., Ludewig, Burkhard, Blakqori, Gjon, Gjon Blakqori, Ludewig Burkhard, Burkhard Ludewig, Cervantes-Barragán, Luisa, Weber Friedemann, Thiel, Volker, Thomas Kuri, Ludewig, B., Thiel, V., Züst, Roland, Blakqori Gjon, Züst Roland, Cervantes-Barragán Luisa, Cervantes-Barragán L, Thiel V, Ludewig B, Kuri T, Züst R, Weber F, Blakqori G   +33 more
core   +2 more sources

Engineering a mouse-adapted SADS-CoV and establishing a neonatal mouse model to study its infection

mBio
Swine acute diarrhea syndrome coronavirus (SADS-CoV) is an emerging bat-origin alphacoronavirus causing severe disease in neonatal piglets, with significant economic losses to the swine industry.
Hanyu Zhang, Mengdi Zhang, Jiaru Zhou, Pengfei Li, Ran Jing, Hongmei Zhu, Yifei Lang, Qigai He, Mengjia Zhang, Wentao Li   +9 more
doaj   +1 more source

Evolution of Point‐of‐Care Nucleic Acid Testing: From Amplification Chemistry to Intelligent and Data‐Driven Systems for Public Health

Aggregate, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in integrated point‐of‐care testing (POCT) systems for public health, encompassing isothermal nucleic acid amplification, CRISPR‐based signal amplification, device integration, and chemometric/artificial intelligence‐assisted data interpretation, with applications in infectious disease surveillance, food and ...
Yan Du, Jiaqi Li, Jinghong Li
wiley   +1 more source

Safeguarding a Flagship Species: Integrated Surveillance of Cross‐Species Pathogen Transmission in Giant Panda Ecosystems

Ecology and Evolution, Volume 16, Issue 3, March 2026.
Emerging infectious diseases increasingly threaten giant pandas and cohabiting species. This review analyzes pathogen transmission risks from domestic animals, wildlife, and vectors and proposes an integrated genomic surveillance framework for early warning and biodiversity conservation.
Xiaoli Sun, Yi Peng, Xiaoye Hao, Rong Dong, Zhilin Wang, Le Wang, Chengdong Wang, Xiangdong Wu, Zheng Chen, Wenbo Zhang, Xiaoli Tang   +10 more
wiley   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source

Development and Diagnostic Application of Monoclonal Antibodies Against Swine Acute Diarrhea Syndrome Coronavirus (SADS-CoV) [PDF]

, 2020
Swine Acute Diarrhea Syndrome Coronavirus (SADS-CoV) is a member of the Coronaviridae family. The virus is associated with severe small intestine inflammation and diarrhea in suckling piglets.
Kroeger, Molly
core   +1 more source

Fangchinoline (2021–2026): A Multitarget Bisbenzylisoquinoline Alkaloid With Emerging Anti‐Infective Potential

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Background Fangchinoline (FC) is a bisbenzylisoquinoline alkaloid reported mainly from the traditional Chinese medicinal plant, Stephania tetrandra. FC has garnered scientific attention because of its wide‐ranging biological properties and multitargeted mechanisms of action.
Alaa Sirwi, Hagar M. Mohamed, Gamal A. Mohamed, Basma G. Eid, Hossam M. Abdallah, Sabrin R. M. Ibrahim, Priya Gusain   +6 more
wiley   +1 more source

Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome [PDF]

, 2007
The severe acute respiratory syndrome coronavirus (SARS-CoV) genome is predicted to encode 14 functional open reading frames, leading to the expression of up to 30 structural and non-structural protein products.
Brunn, Albrecht von, Teepe, Carola, Caroline C Friedel, Ralph Baric, Haas, Jürgen, von Brunn, Albrecht, Simpson Jeremy C., Jeremy C. Simpson, Simpson, Jeremy C., Ralf Zimmer, Roberts, Rhonda, Carola Teepe, Rainer Pepperkok, Baric Ralph, Haas Jürgen, Simpson, Jeremy, Zimmer, Ralf, Zimmer Ralf, Caroline C. Friedel, Friedel, Caroline C., Haas, Juergen, Teepe Carola, Albrecht von Brunn, Rhonda Roberts, Jürgen Haas, Friedel Caroline C., Pepperkok Rainer, Pepperkok, Rainer, Roberts Rhonda, Baric, Ralph, Jeremy C Simpson, von Brunn Albrecht   +31 more
core   +1 more source

Genetic Diversity, Recombination, and Pathogenicity of Porcine Epidemic Diarrhea Virus Strains Circulating in China During 2023–2024

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV) is an enteric alphacoronavirus that causes severe diarrhea and high mortality in neonatal piglets, posing a persistent threat to the global swine industry. Despite extensive vaccination, PEDV continues to circulate in China, underscoring the need for updated molecular epidemiological surveillance.
Yunlei Cao, Ahui Cui, Xin Chen, Yang Cheng, Rongfeng Tang, Hui Zeng, Yuchen Li, Qian Yang, Linzhu Ren   +8 more
wiley   +1 more source

Human monoclonal antibody combination against SARS coronavirus : synergy and coverage of escape mutants [PDF]

, 2006
Background: Experimental animal data show that protection against severe acute respiratory syndrome coronavirus (SARS-CoV) infection with human monoclonal antibodies (mAbs) is feasible.
Cox Freek, Doerr, Hans Wilhelm, Brink, Edward van den, van den Brink Edward N, Hans Wilhelm Doerr, ter Meulen Jan, Doerr Hans Wilhelm, Cheung, Chung Y., de Kruif John, Jaap Goudsmit, Leo L. M., Poon, Leo L M Poon, Marissen Wilfred E, Marissen, Wilfred E., Poon Leo L. M, Chow Vincent T, Chung Y Cheung, Wolfgang Preiser, Preiser, Wolfgang, Van Deventer, E, Bogaards Johannes A, Freek Cox, Wilfred E Marissen, Els van Deventer, Joseph S M Peiris, Chow, Tak-Kwong Vincent, Bakker, Arjen Q., Leung, CSW, Goudsmit Jaap, Deventer, Els van, Kruif, John de, De Kruif, J, John de Kruif, Cynthia S W Leung, Jan ter Meulen, Bogaards, Johannes A., Cox, F, Preiser Wolfgang, Cox, Freek, Goudsmit, J, Peiris Joseph S. M, Poon, LLM, Cheung, CY, Johannes A Bogaards, Doerr, HW, van Deventer Els, Marissen, WE, Bakker Arjen Q, Leung Cynthia S. W, Chow, VT, Edward N van den Brink, Bogaards, JA, Vincent T Chow, Arjen Q Bakker, Cheung Chung Y, Van Den Brink, EN, Peiris, Joseph Sriyal Malik, Ter Meulen, J, Leung, Cynthia S. W., Goudsmit, Jaap, Peiris, JSM, Meulen, Jan ter, Bakker, AQ, Preiser, W, Poon L.L.M., Van Den Brink E.N., Preiser W., Leung C.S.W., Marissen W.E., Chow V.T., Bakker A.Q., Bogaards J.A., Goudsmit J., Van Deventer E., Doerr H.W., Cheung C.Y., Ter Meulen J., Peiris J.S.M., Cox F., De Kruif J.   +79 more
core   +1 more source