Results 21 to 30 of about 10,523 (171)

Synthesis, Structural Characterization, and In Silico ADMET Testing of Novel 17β-Acetoxy-17α-(Pyridin-2-yl) Estrane Derivatives

Medical Sciences Forum, 2022
Steroidal compounds that contain a heterocyclic ring or heteroatom in their structure usually possess good anticancer activity. The main goal of modern medicinal chemistry is to find new potent agonists or antagonists of naturally occurring hormones for ...
Milica Stevanović, Ivana Kuzminac
doaj   +1 more source

Xanthones, A Promising Anti-Inflammatory Scaffold: Structure, Activity, and Drug Likeness Analysis

Molecules, 2020
Inflammation is the body’s self-protective response to multiple stimulus, from external harmful substances to internal danger signals released after trauma or cell dysfunction.
Zheling Feng, Xiuqiang Lu, Lishe Gan, Qingwen Zhang, Ligen Lin   +4 more
doaj   +1 more source

Synthesis, In-vitro Antimalarial Activity and In silico Molecular Docking Study of Amino Chalcone Derivatives from 1-(2-aminophenyl)-3-(4- substituted-phenyl) prop-2-en-1-one and Dihydroquinolone Derivatives [PDF]

Journal of Advanced Pharmacy Research, 2023
Background: Malaria is one of the major global health problems in developing countries and faced to the increased resistance of Plasmodium falciparum against existing malarial agents, it is important to look for new antimalarial compounds that will be ...
Arnold Mulula, Abdel Bouzina, Joachim Nsomue, Hugues Mambu, Milka Tshingamb, Ahmed Zaki   +5 more
doaj   +1 more source

A computational chemistry-driven hypothesis on the mode of action of Hipposudoric Acid and related analogues - Supplementary Material

, 2022
SwissADME results 
Stephen P. Wren (352005), Islam M Araar (13013752)   +1 more
core   +2 more sources

Prediction of Pharmacokinetics Parameter and Molecular Docking Study of Antidiabetic Compounds from Syzygium polyanthum and Syzygium cumini

Jurnal Kimia Sains dan Aplikasi, 2020
Syzygium polyanthum leaf extract and Syzygium cumini herbs extract have been reported to have antidiabetic activity. This study aimed to predict the molecular target of chemical constituents of S. polyanthum and S.
Widia Wati, Gunawan Pamudji Widodo, Rina Herowati   +2 more
doaj   +1 more source

Table of SwissADME Analysis of Flavonoid Compounds

, 2021
Tabulation of SwissADME Analysis for Journal Article: In Silico Study of Flavonoid Compound: Utilization of Molecular Simulation to Discover Drug Candidate for COVID ...
Wisnumurti, Rafi Firdaus
core   +1 more source

A Supramolecular Approach to Structure-Based Design with A Focus on Synthons Hierarchy in Ornithine-Derived Ligands: Review, Synthesis, Experimental and in Silico Studies

Molecules, 2020
The success of innovative drugs depends on an interdisciplinary and holistic approach to their design and development. The supramolecular architecture of living systems is controlled by non-covalent interactions to a very large extent.
Joanna Bojarska, Milan Remko, Martin Breza, Izabela D. Madura, Krzysztof Kaczmarek, Janusz Zabrocki, Wojciech M. Wolf   +6 more
doaj   +1 more source

Physicochemical and pharmacokinetics of the compounds 8a-g using SwissADME server.

, 2023
Physicochemical and pharmacokinetics of the compounds 8a-g using SwissADME server.
Fars K. Alanazi (1549927), Awwad A. Radwan (11939566), Mohammad Raish (86736)   +2 more
core   +1 more source

Radar plot showing the physicochemical properties of the selected compounds against FtsZ calculated through SwissADME server (http://www.swissadme.ch/index.php).

, 2023
Radar plot showing the physicochemical properties of the selected compounds against FtsZ calculated through SwissADME server (http://www.swissadme.ch/index.php).
Bader Saud Alotaibi (16907866)
core   +1 more source

Sintesis Senyawa 4-(Dimetilamino)calkon Menggunakan Microwave-Assisted Organic Synthesis (MAOS) dengan Variasi Konsentrasi NaOH dan Prediksi Profil Farmakokinetik

Alchemy, 2023
Senyawa calkon dan turunannya mempunyai aktivitas farmakologi dengan aplikasi yang luas, karenya sintesis senyawa tersebut perlu dipelajari. Oleh karena itu, penelitian ini bertujuan untuk mensintesis 4-(dimetilamino)calkon dari dalam suasana basa dengan
Iin Narwanti, Aisyah Khairani Hidayati
doaj   +1 more source