Results 41 to 50 of about 10,449 (207)
Evaluasi Parameter Fisikokimia, Farmakokinetika, dan Farmakodinamika Senyawa Fisetin Dalam Desain Obat [PDF]
Fisetin is a flavonoid with flavonol framework found in various fruits and vegetables such as strawberries, apples, persimmons, lotus root, grapes, onions, kiwi, peaches, and others.
Fadlan, Arif +2 more
core +2 more sources
Escherichia coli and Staphylococcus aureus are important agents of urinary tract infections that can often evolve to severe infections. The rise of antibiotic-resistant strains has driven the search for novel therapies to replace the use or act as ...
Valério Monteiro-Neto +16 more
doaj +1 more source
The resistance of the P. falciparum strain to some of the antimalarial drugs has been a dominant dilemma facing the treatment of this fetid disease. This necessitates the detection and development of new antimalarial agents targeting the P. falciparum.
Ibrahim, Zakari Yau +3 more
openaire +2 more sources
Stimulatory Effects of Lycium shawii on Human Melanocyte Proliferation, Migration, and Melanogenesis: In Vitro and In Silico Studies [PDF]
There is no first-line treatment for vitiligo, a skin disease characterized by a lack of melanin produced by the melanocytes, resulting in an urgent demand for new therapeutic drugs capable of stimulating melanocyte functions, including melanogenesis. In
Al-Eidi, Hamad +10 more
core +2 more sources
Fragment-Based Drug Discovery of SARS-CoV-2 Therapeutics [PDF]
During the COVID-19 pandemic, the usual drug development timeline has been substantially condensed. This shortened timeline aims to allow for a safe and effective therapy to be discovered as soon as possible as the number of global COVID cases rise ...
Johnson, Hannah, \u2722
core +1 more source
Development and optimization of solid lipid nanoparticles loaded with Glimepiride for enhancement of pharmacokinetic and therapeutic applicability [PDF]
Diabetes mellitus, particularly type 2 diabetes, is a growing global health concern. Glimepiride, a widely used antidiabetic drug, faces challenges related to its poor aqueous solubility and short half-life, impacting its pharmacokinetics and therapeutic
Brijesh Kumar, Nikhil Kumar, Vivek Kumar Sisodia, Arvind Rathour, Vijay Kumar
core +2 more sources
DNA Damage prevention by the use of Computational Designed Microlpastics adsorbing Chemicals.
Cancer development is driven by uncontrolled cellular proliferation resulting from the accumulation of genetic mutations. One of the most well-studied mechanisms behind these mutations is DNA damage.
Khadija Abbas Sahan, Zahraa Abbas Sahan
doaj +1 more source
The development of new drug-like molecules based on 7-R-8-hydrazine derivatives of 1,3-dimethylxanthine is promising in view of the known pharmacological effect of theophylline and functional hydrazine derivatives.
L. M. Mosula +2 more
doaj +1 more source
The drug likeness analysis of anti-inflammatory clerodane diterpenoids
Inflammation is an active defense response of the body against external stimuli. Long term low-grade inflammation has been considered as a deteriorated factor for aging, cancer, neurodegeneration and metabolic disorders.
Zheling Feng +3 more
doaj +1 more source
Presently, there are no approved drugs or vaccines to treat COVID-19 which has spread to over 200 countries and is responsible for over 3,65,000 deaths worldwide.
Biswal, Himansu S. +4 more
core +1 more source

