Results 51 to 60 of about 10,449 (207)
Annals of Mechnikov's InstituteВступ. Важливість іn silico аналізу була визнана через високу достовірність прогнозованих результатів. Віртуальний скринінг базується на залежності властивостей молекули від її структури. Деякі Інтернет-ресурси дають змогу спрогнозувати поведінку сполуки
Liudmila Mosula +2 more
doaj +1 more source
Synthesis, in-vitro inhibition of cyclooxygenases and in silico studies of new isoxazole derivatives
Frontiers in Chemistry, 2023 Isoxazole belongs to the class of five-membered heterocyclic compounds. The process of developing new drugs has significantly gained attention due to inadequate pharmacokinetic and safety attributes of the available drugs.
Waqas Alam +6 more
doaj +1 more source
Activity of Secondary Metabolites of Momordica Charantia as a DNA Gyrase Inhibitor of Helicobacter Pylori: Homology Modelling and Molecular Docking [PDF]
, 2022 Helicobacter pylori can induce gastritis, ulcers, and gastric cancer. H. pylori is also responsible for causing oropharynx, endocrine, respiratory, central nervous system, eye, and reproductive system diseases. Treatment of H.
Anggraeni, Amaliyah Dina +1 more
core +2 more sources
Revue Congolaise des Sciences et TechnologiesLa pharmacocinétique et la toxicologie cutanées sont importantes en cosmétologie, car les effets nocifs de la lumière ultraviolette nécessitent une photoprotection externe, comme les crèmes solaires contenant des filtres solaires.
Christian V. Mulombela +11 more
doaj +1 more source
Potensi Senyawa Hidrazon berbasis Turunan 2-Tiohidantoin dan Hidrazida sebagai Inhibitor Protein E6 pada Kanker Serviks secara In Silico [PDF]
, 2022 Setiap tahun, prevalensi penyakit kanker leher rahim di dunia semakin meningkat. Kanker serviks dapat terjadi akibat infeksi Human Papillomavirus (HPV).
Abidiy, Syafri Izzat +5 more
core +2 more sources
Advanced Science, EarlyView.Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green +15 more
wiley +1 more source
Penelusuran Senyawa Inhibitor Dipeptidyl Peptidase-4 (DPP-4 Inhibitors atau Gliptin) Potensial untuk Diabetes Melitus Tipe 2 melalui Pendekatan In Silico dengan Evaluasi Profil ADME via SwissADME [PDF]
This study aims to identify the potential of in silico methods as a rapid and cost-effective approach for the initial screening of DPP-4 inhibitor candidates, as well as to identify compounds that meet drug-likeness criteria and exhibit good ADME ...
Apriyani Pramudiyawati Yunar
core +2 more sources
Profil ADME dari Entitas Molekul Baru yang Disetujui oleh FDA Tahun 2021: Suatu Kajian In Silico [PDF]
, 2022 Aspek farmakokinetik dan farmakodinamik yang diwakili oleh sifat adsorpsi, distribusi, metabolisme, ekskresi (ADME) merupakan syarat penting suatu obat dapat menuju targetnya.
Arief, Ihsanul, Hairunnisa, Hairunnisa
core +1 more source
Molecules, 2023 Non-small cell lung cancer (NSCLC) is the most common form of lung cancer. Despite the existence of various therapeutic options, NSCLC is still a major health concern due to its aggressive nature and high mutation rate.
Ayed A. Dera +6 more
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.This study applies QSAR‐based new approach methodologies to 90 synthetic tattoo and permanent makeup pigments, revealing systemic links between their physicochemical properties and absorption, distribution, metabolism, and elimination profiles. The correlation‐driven analysis using SwissADME, ChemBCPP, and principal component analysis uncovers insights
Girija Bansod +10 more
wiley +1 more source