From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and realization of a compact and multi-purpose passively Q-switched ND:YAG laser system [PDF]
In this paper, a passively Q-switched pulsed Nd:YAG laser system is designed and realized for defense applications. Our previously published generalized mathematical model for passively Q-switched lasers is used to help extract the design parameters of ...
Adel Mohamed
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
In response to the challenge of existing wireless communication anti-jamming methods in effectively handling unknown jamming, this paper proposes a multi-parameter control anti-jamming algorithm for wireless communication systems based on the Linear ...
Hang Yao +4 more
doaj +1 more source
Robust Semipassivity and Practical Stability for Uncertain Switched Nonlinear Systems
This paper addresses several issues including robust semipassivity and practical stability analysis for a switched nonlinear system with structural uncertainties.
Shuo Liu, Hongbo Pang
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Performance analysis of a Master/Slave switched Ethernet for military embedded applications [PDF]
Current military communication network is a generation old and is no longer effective in meeting the emerging requirements imposed by the next generation military embedded applications. A new communication network based upon Full Duplex Switched Ethernet
Frances, Fabrice +5 more
core +1 more source
Fuzzy Resilient Control of DC Microgrids with Constant Power Loads Based on Markov Jump Models
This paper addresses the fuzzy resilient control of DC microgrids with constant power loads. The DC microgrid is subject to abrupt parameter changes which are described by the Markov jump model.
Wei Hu +4 more
doaj +1 more source
Limited Rolling Time Domain-Based Hybrid Tracking Control for Injection Molding Process
In this paper, a limited rolling time domain-based hybrid tracking control method for injection and packing-holding phase in the injection molding process is proposed. A more flexible controller is designed by adding the adjustable weighting coefficient.
Jingxian Yu, Qiyuan Zhang
doaj +1 more source

