Results 61 to 70 of about 1,139,338 (253)
Efforts to minimise the size and material usage of power converters are reflected in efforts to increase the switching frequency. The problem is that semiconductor switching losses are proportional to the switching frequency, so it is necessary to find ...
Pástor Marek +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
With current mature optical device technology for processing optical codes (OCs), OC label switchings now become promising for the future photonic networkings.
CINCOTTI, GABRIELLA +4 more
core
Modulated Model-Free Predictive Control With Minimum Switching Losses for PMSM Drive System
A modulated model-free predictive control with minimum switching losses (MSL-MMFPC) is proposed to improve the steady-state performance and reduce the switching losses for a permanent magnet synchronous motor (PMSM) drive system.
Yuchen Wang +4 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Multistep MPC of dual inverter for switching losses optimization
A novel control method based on model predictive control (MPC) dedicated to dual inverter (DI) control with minimization of switching losses is introduced.
Martin Votava +5 more
core +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
System-Level Switching-Frequency Trade-Offs in a High-Fundamental-Frequency MW-Class PMSM Drive
While high-speed, high-specific-power permanent-magnet synchronous machines (PMSMs) are critical for emerging aerospace and mobility applications, the existing literature does not provide a comprehensive measurement-based analysis of machine– ...
Huseyin Tayyer Canseven +8 more
doaj +1 more source
Novel ZVS S-TCM Modulation of Three-Phase AC/DC Converters
For three-phase AC-DC power conversion, the widely-used continuous current mode (CCM) modulation scheme results in relatively high semiconductor losses from hard-switching each device during half of the mains cycle.
Michael Haider +7 more
doaj +1 more source

