Results 91 to 100 of about 238,540 (305)

STRUCTURAL CHANGE IN THE BRAZILIAN DEMAND FOR IMPORTS: A regime switching approach [PDF]

The aim of the present paper is to apply a Markov Switching model to check the characteristics of the Brazilian demand for imports equation based on annual data from 1947 to 2002 and on quarterly data from 1978:I to 2002:II.
M. Portugal, I.A. de Morais
core  

Rotational magnetoelectric switching in orthorhombic multiferroics

npj Computational Materials
Controlling the direction of ferromagnetism and antiferromagnetism by an electric field in single-phase multiferroics will open the door to the next generation of devices for spintronics and electronics.
Xu Li, Hao Tian, Lan Chen, Hongjun Xiang, Jun-Ming Liu, L. Bellaiche, Di Wu, Yurong Yang   +7 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Mathematical Modeling of Bipolar Resistive Switching Mechanism

, 2014
Recently, transition metal oxide materials showing bipolar resistive switching have attracted deep interest. These materials have an application as resistive random access memory (RRAM) which shows advantages over capacitance based RAMs and even other ...
Manasi H. Kulkarni (7977113)
core  

Homogeneous switching mechanism in pure polyvinylidene fluoride ultrathin films

, 2015
International audiencePolarization switching kinetics is one of the key issues for future development of nanoelectronic devices based on ferroelectrics.
Yuan, G.L., X.F., Bai, Meng, X.J., Dkhil, B, Liu, Yi, Sun, J.L., Chu, J.H., Chen, L.F., Sun, Sh, Wang, J.L., Tian, B.B.   +10 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The influence of supplementary health insurance on switching behaviour: evidence on Swiss data [PDF]

This paper focuses on the switching behaviour of sickness fund enrolees in the Swiss health insurance system. Even though the new Federal Law on Social Health Insurance (LAMal) was implemented in 1996 to promote competition among health insurers in basic
Brigitte Dormont, Pierre-Yves Geoffard, Karine Lamiraud   +2 more
core  

Gait Analysis and Simulation of a Multi-mode 4-UPU Mechanism

Jixie chuandong, 2022
In order to adapt to various environmental requirements， a new multi-mode mechanism with series-parallel switching function is proposed. The mechanism can change its structural constraints according to the actual working conditions to form different ...
Bing Ding, Chunyan Zhang, An Ping, Xinyue Yu   +3 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source