Results 81 to 90 of about 238,540 (305)

Amplification effects of the send rate of TCP connection through an optical burst switching network

, 2005
This paper investigates support for TCP RENO flows in an Optical Burst Switching (OBS) network. In particular we evaluate the TCP send-rate, i.e., the amount of data sent per time unit taking into account the burst assembly mechanism at the edge nodes of
Listanti, M, Andrea Detti, DETTI, ANDREA, LISTANTI, Marco, Listanti, M., Detti, A   +5 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Dynamical switching of an electromagnetically driven compliant bistable mechanism

, 2014
Dynamical switching behaviors of a compliant bistable mechanism driven by electromagnetic force are investigated. The bistability of the mechanism originates from combined tension and bending of the beam structures.
Hsieh, Y.H., Pham, H.T., Wang, D.A., 王東安   +3 more
core   +1 more source

Possible Factor Xa Resistance in a Patient Who Failed Apixaban and Rivaroxaban

Clinical Case Reports
This article aims to discuss the literature on switching to an anticoagulant with a different mechanism of action in case of treatment failure. We present a patient with atrial fibrillation who incurred an embolic stroke despite adequate anticoagulation ...
Ola Ali, Awab Elnaeem, Manmeet Kaur, Nitisha Thatikonda, Julia Aigbogun, A. K. M. Muktadir   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Solid state optical conjugated polymer amplifier; with ultrafast gain switching

, 2008
Conjugated polymers are organic materials which are attractive as optoelectronic devices because they have a combination of broad band emission, high gain, versatility in processing, are ductile and can be electrically pumped.
Amarasinghe, Dimali C. V.
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Conductive polymer switching mechanism for high power current-limiting applications

, 2009
Various thermoplastic and thermo-set based polymers, blended with acetylene carbon blacks and graphite fillers to form electrically conductive polymers, were investigated to determine the switching mechanism under high power short-circuit fault ...
J. J. Shea
core   +1 more source

Sub-nanosecond polarization switching with anomalous kinetics in vdW ferroelectric WTe2

Nature Communications
Recently discovered “sliding ferroelectrics” exhibit distinct polarization origin and switching mechanism compared to conventional ferroelectric materials. However, a clear understanding of the polarization switching kinetics remains lacking.
Yinxin Bai, Zhichao Yu, Zeyu Guan, Junjiang Tian, Chuanshou Wang, Xiaodong Yao, Yihao Yang, Yunlin Lei, Jingbo Xu, Chenhao Liu, Jinlong Zhu, Yuchen Tu, Shengchun Shen, Hongjun Xiang, Xiaoguang Li, Changsong Xu, Junling Wang   +16 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source