Results 71 to 80 of about 3,394,183 (296)
Early childhood caries in Switzerland: a marker of social inequalities
BackgroundEarly childhood caries (ECC) is a marker of social inequalities worldwide because disadvantaged children are more likely to develop caries than their peers.
Stéphanie Baggio +4 more
semanticscholar +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Journalists in Switzerland: Structures and attitudes revisited
It is often stated that journalism and the media are going through some fundamental changes. In this article, we present a description of the journalists in Switzerland, based on a nation-wide survey conducted in 2015.
Filip Dingerkus +4 more
doaj +1 more source
Efeitos da terapia de extrato de Camellia sinensis (L.) Kuntze (Chá verde) e fotobiomodulação em camundongos Swiss injetados com veneno de Bothrops alternatus / Effects of Camellia sinensis (L.) Kuntze (green tea) extract therapy and photobiomodulation in Swiss mice injected with Bothrops alternatus venom [PDF]
Doroty Mesquita Dourado +6 more
openalex +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Monthly RUSLE soil erosion risk of Swiss grasslands
This study presents the first mapping of soil erosion risk modelling based on the Revised Universal Soil Loss Equation (RUSLE) at a sub-annual (monthly) temporal resolution and national scale (100 m spatial resolution).
Simon Schmidt +2 more
doaj +1 more source
The ongoing digitization gives rise to the possibility for administrations to offer citizen participation digitally by using so-called e-participation offerings.
Damaris Fischer +5 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The question studied within the framework of the Wilhelminaoord Workshop was: In which way the mould material does influence the cast structure of a bronze object?
Emanuela Jochum Zimmerman +2 more
doaj
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source

