Ins and Outs of Rocker Switch Mechanism in Major Facilitator Superfamily of Transporters [PDF]
Membranes, 2023 The major facilitator superfamily (MFS) of transporters consists of three classes of membrane transporters: symporters, uniporters, and antiporters. Despite such diverse functions, MFS transporters are believed to undergo similar conformational changes ...
Stephanie Sauve +3 more
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Functional Roles of the Conserved Amino Acid Sequence Motif C, the Antiporter Motif, in Membrane Transporters of the Major Facilitator Superfamily [PDF]
Biology, 2023 The biological membrane surrounding all living cells forms a hydrophobic barrier to the passage of biologically important molecules. Integral membrane proteins called transporters circumvent the cellular barrier and transport molecules across the cell ...
Manuel F. Varela +4 more
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Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters [PDF]
FEBS Open BioThe cation‐chloride cotransporter (CCC) family includes ion symporters that cotransport monovalent cations and Cl−, playing a crucial role in controlling cytoplasmic ion content.
Satoshi Fudo +4 more
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Allosteric effects of the coupling cation in melibiose transporter MelB [PDF]
eLifeThe major facilitator superfamily (MFS) transporters play significant roles in human health and disease. Salmonella enterica serovar Typhimurium melibiose permease (MelBSt) catalyzes the symport of galactosides with Na+, H+, or Li+ and is a prototype of ...
Parameswaran Hariharan +5 more
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Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling [PDF]
eLifeMetabolic pathways are remodeled in response to energy and other homeostatic demands and are dynamically regulated during embryonic development, suggesting a role in guiding cellular differentiation.
Joseph Hanna +14 more
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Sodium Iodide Symporter (NIS) and Thyroid [PDF]
HORMONES, 2002 idase (TPO) and incorporation into tyrosyl residues along the thyroglobulin (Tg) backbone. The thyroid hormones T3 and T4 are synthesized by coupling of two iodotyrosine residues and stored in the colloid. All of these steps are stimulated by pituitary-derived thyroid stimulating hormone (TSH), which interacts with the TSH receptor at the basolateral ...
Christine Spitzweg, John C. Morris
openalex +3 more sources
The joint action of yeast eisosomes and membraneless organelles in response to ethanol stress [PDF]
HeliyonElevated ethanol concentrations in yeast affect the plasma membrane. The plasma membrane in yeast has many lipid-protein complexes, such as Pma1 (MCP), Can1 (MCC), and the eisosome complex.
Camila Moreira Pinto +7 more
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Mosaic Evolution of Membrane Transporters in Galdieriales [PDF]
PlantsMembrane transporters are vital for solute movement and localisation across cellular compartments, particularly in extremophilic organisms such as Galdieriales.
Claudia Ciniglia +6 more
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Control of Conformational Transitions by the Conserved GX<sub>9</sub>P Motif in the Fifth Transmembrane Domain of Neurotransmitter Sodium Symporters. [PDF]
Int J Mol SciZhang X, Xu Y, Chen Q, Li C, Zhang YW.
europepmc +3 more sources
pH Regulation of Electrogenic Sugar/H+ Symport in MFS Sugar Permeases. [PDF]
PLoS ONE, 2016 Bacterial sugar symporters in the Major Facilitator Superfamily (MFS) use the H+ (and in a few cases Na+) electrochemical gradients to achieve active transport of sugar into the cell.
Andre Bazzone +3 more
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