Results 41 to 50 of about 7,540 (181)

Dimerization of the Sodium/Iodide Symporter

Thyroid®, 2019
Background: The ability of thyroid follicular epithelial cells to accumulate iodide via the sodium/iodide symporter (NIS) is exploited to successfully treat most thyroid cancers, although a subset of patients lose functional NIS activity and become unresponsive to radioiodide therapy, with poor clinical outcome.
Thompson, Rebecca J., Fletcher, Alice, Brookes, Katie, Nieto, Hannah, Alshahrani, Mohammed M., Mueller, Jonathan W., Fine, Nicholas H.F., Hodson, David J., Boelaert, Kristien, Read, Martin L., Smith, Vicki E., McCabe, Christopher J.   +11 more
openaire   +2 more sources

The yeast H+-ATPase Pma1 promotes Rag/Gtr-dependent TORC1 activation in response to H+-coupled nutrient uptake

eLife, 2018
The yeast Target of Rapamycin Complex 1 (TORC1) plays a central role in controlling growth. How amino acids and other nutrients stimulate its activity via the Rag/Gtr GTPases remains poorly understood.
Elie Saliba, Minoas Evangelinos, Christos Gournas, Florent Corrillon, Isabelle Georis, Bruno André   +5 more
doaj   +1 more source

Metabolic Profiles of Carbohydrates in Streptococcus thermophilus During pH-Controlled Batch Fermentation

Frontiers in Microbiology, 2020
Revealing the metabolic profiles of carbohydrates with their regulatory genes and metabolites is conducive to understanding their mechanism of utilization in Streptococcus thermophilus MN-ZLW-002 during pH-controlled batch fermentation.
Gefei Liu, Yali Qiao, Yanjiao Zhang, Cong Leng, Hongyu Chen, Jiahui Sun, Xuejing Fan, Aili Li, Zhen Feng   +8 more
doaj   +1 more source

Structure, function and plasticity of GABA transporters

Frontiers in Cellular Neuroscience, 2014
GABA transporters belong to a large family of neurotransmitter:sodium symporters. They are widely expressed throughout the brain, with different levels of expression in different brain regions.
Annalisa eScimemi
doaj   +1 more source

About P systems with symport/antiport [PDF]

Soft Computing, 2004
It is proved that four membranes su±ce to P systems with minimal symport/antiport to generate all recursively enumerable sets of numbers. It is also proved that P systems with symport/antiport without maximal par- allelism are equivalent to partially blind counter automata.
openaire   +3 more sources

Employing information theoretic measures and mutagenesis to identify residues critical for drug-proton antiport function in Mdr1p of Candida albicans. [PDF]

PLoS ONE, 2010
By employing information theoretic measures, this study presents a structure and functional analysis of a multidrug-proton antiporter Mdr1p of Candida albicans.
Khyati Kapoor, Mohd Rehan, Andrew M Lynn, Rajendra Prasad   +3 more
doaj   +1 more source

Genome-Wide Identification and Transcript Analysis Reveal Potential Roles of Oligopeptide Transporter Genes in Iron Deficiency Induced Cadmium Accumulation in Peanut

Frontiers in Plant Science, 2022
The oligopeptide transporter (OPT) family is a group of proton-coupled symporters that play diverse roles, including metal homeostasis. However, little is known about this family of peanuts.
Chaohui Wang, Xueqin Wang, Jinxiu Li, Junhua Guan, Zengjing Tan, Zheng Zhang, Gangrong Shi   +6 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

P Systems with Symport/Antiport of Rules

J. Univers. Comput. Sci., 2004
JUCS - Journal of Universal Computer Science Volume Nr.
Cavaliere M., Genova D.
openaire   +5 more sources

Molecular determinants for the thermodynamic and functional divergence of uniporter GLUT1 and proton symporter XylE. [PDF]

PLoS Computational Biology, 2017
GLUT1 facilitates the down-gradient translocation of D-glucose across cell membrane in mammals. XylE, an Escherichia coli homolog of GLUT1, utilizes proton gradient as an energy source to drive uphill D-xylose transport.
Meng Ke, Yafei Yuan, Xin Jiang, Nieng Yan, Haipeng Gong   +4 more
doaj   +1 more source