Results 31 to 40 of about 13,548 (269)
Journal of Fungi, 2021 The three families of yeast plasma membrane potassium influx transporters are represented in Candida albicans: Trk, Acu, and Hak proteins. Hak transporters work as K+-H+ symporters, and the genes coding for Hak proteins are transcriptionally activated ...
Francisco J. Ruiz-Castilla +3 more
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Anion Selectivity by the Sodium Iodide Symporter [PDF]
Endocrinology, 2003 Abstract The iodide transporter of the thyroid (NIS) has been cloned by the group of Carrasco. The NIS-mediated transport was studied by electrophysiological methods in NIS-expressing Xenopus oocytes. Using this method, the anion selectivity of NIS was different from that previously reported for thyroid cells, whereas perchlorate and ...
Van Sande, Jacqueline +6 more
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Nature Communications, 2020 Neurotransmitter:sodium symporters (NSS) serve as targets for drugs including antidepressants and psychostimulants. Here authors report the X-ray structure of the prokaryotic NSS member, LeuT, in a Na+/substrate-bound, inward-facing occluded conformation
Kamil Gotfryd +14 more
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A chemiosmotic mechanism of symport [PDF]
Proceedings of the National Academy of Sciences, 2015 Lactose permease (LacY), a paradigm for the largest family of membrane transport proteins, catalyzes the coupled translocation of a galactoside and an H + across the Escherichia coli membrane (galactoside/H + symport).
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A symporter’s secrets shown [PDF]
Journal of General Physiology, 2017 New JGP study explores the thermodynamic cycle and cation preference of the sugar symporter MelB.
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The Role of Mfsd2a in Nervous System Diseases
Frontiers in Neuroscience, 2021 Major facilitator superfamily (MFS) is the maximum and most diversified membrane transporter, acting as uniporters, symporters and antiporters. MFS is considered to have a good development potential in the transport of drugs for the treatment of brain ...
Bei Huang +3 more
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Co-transport-induced instability of membrane voltage in tip-growing cells [PDF]
Phys. Rev. Lett. 95 (2005) 208105, 2005 A salient feature of stationary patterns in tip-growing cells is the key role played by the symports and antiports, membrane proteins that translocate two ionic species at the same time. It is shown that these co-transporters destabilize generically the membrane voltage if the two translocated ions diffuse differently and carry a charge of opposite ...
arxiv +1 more source
Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+ symporters
Journal of molecular medicine, 2015 Since Otto Warburg reported the ‘addiction’ of cancer cells to fermentative glycolysis, a metabolic pathway that provides energy and building blocks, thousands of studies have shed new light on the molecular mechanisms contributing to altered cancer ...
Ibtissam Marchiq, J. Pouysségur
semanticscholar +1 more source
Dimerization of the Sodium/Iodide Symporter
Thyroid, 2019 Background: The ability of thyroid follicular epithelial cells to accumulate iodide via the sodium/iodide symporter (NIS) is exploited to successfully treat most thyroid cancers, although a subset of patients lose functional NIS activity and become unresponsive to radioiodide therapy, with poor clinical outcome.
Mohammed Alshahrani +23 more
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New Choice for Small Universal Devices: Symport/Antiport P Systems [PDF]
EPTCS 1, 2009, pp. 235-242, 2009 Symport/antiport P systems provide a very simple machinery inspired by corresponding operations in the living cell. It turns out that systems of small descriptional complexity are needed to achieve the universality by these systems. This makes them a good candidate for small universal devices replacing register machines for different simulations ...
arxiv +1 more source