Using small molecules to facilitate exchange of bicarbonate and chloride anions across liposomal membranes [PDF]
Bicarbonate is involved in a wide range of biological processes, which include respiration, regulation of intracellular pH and fertilization. In this study we use a combination of NMR spectroscopy and ion-selective electrode techniques to show that the ...
A Fürstner+41 more
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Evolutionary Relationship between K+ Channels and Symporters [PDF]
The hypothesis is presented that at least four families of putative K(+) symporter proteins, Trk and KtrAB from prokaryotes, Trk1,2 from fungi, and HKT1 from wheat, evolved from bacterial K(+) channel proteins. Details of this hypothesis are organized around the recently determined crystal structure of a bacterial K(+) channel: i.
Evert P. Bakker+4 more
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Glucose Transport in Escherichia coli: From Basics to Transport Engineering
Escherichia coli is the best-known model for the biotechnological production of many biotechnological products, including housekeeping and heterologous primary and secondary metabolites and recombinant proteins, and is an efficient biofactory model to ...
Ofelia E. Carreón-Rodríguez+3 more
doaj +1 more source
Thyroid Na+/I− Symporter [PDF]
The rat thyroid Na+/I- symporter (NIS) was expressed in Xenopus laevis oocytes and characterized using electrophysiological, tracer uptake, and electron microscopic methods. NIS activity was found to be electrogenic and Na+-dependent (Na+ >> Li+ >> H+).
Sepehr Eskandari+5 more
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Long-term prenatal stress increases susceptibility of N-methyl-D-aspartic acid-induced spasms in infant rats [PDF]
PurposeInfantile spasms, also known as West syndrome, is an age-specific epileptic seizure. Most patients with this condition also exhibit delayed development.
Hyeok Hee Kwon+4 more
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Background Panax notoginseng is a medicinally important Chinese herb with a long history of cultivation and clinical application. The planting area is mainly distributed in Wenshan Prefecture, where the quality and safety of P.
Guan-Hua Cao+8 more
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MCT1 in Invasive Ductal Carcinoma: Monocarboxylate Metabolism and Aggressive Breast Cancer. [PDF]
Introduction: Monocarboxylate transporter 1 (MCT1) is an importer of monocarboxylates such as lactate and pyruvate and a marker of mitochondrial metabolism.
Birbe, Ruth C.+14 more
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NRT2.5 a putative sodium dependent high affinity nitrate trasnporter of zostera marina l. [PDF]
Seagrasses are the only group of vascular plants that recolonized the marine environment, possibly the most severe habitat shift ever accomplished by flowering plants.
Botella-Mesa, Miguel Angel+3 more
core
Functional PTB phosphate transporters are present in streptophyte algae and early diverging land plants [PDF]
International audienceTwo inorganic phosphate (Pi) uptake mechanisms operate in streptophytes and chloro-phytes, the two lineages of green plants. PHOSPHATE TRANSPORTER B (PTB) proteins are hypothesized to be the Na + /Pi symporters catalysing Pi uptake ...
Bonnot, Clémence+9 more
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Conformational Space and Dynamics of Sodium-Coupled Symporters [PDF]
Secondary transporters utilize the free energy stored in the sodium gradient to move a solute against a concentration gradient. The transport process involves a sequence of conformational changes that exposes the substrate and ion binding sites alternatively to the extracellular and the intracellular compartment.
Beckstein, O, Sansom, M
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