Results 61 to 70 of about 12,546 (277)

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

General Principles of Secondary Active Transporter Function [PDF]

, 2019
Transport of ions and small molecules across the cell membrane against electrochemical gradients is catalyzed by integral membrane proteins that use a source of free energy to drive the energetically uphill flux of the transported substrate. Secondary active transporters couple the spontaneous influx of a "driving" ion such as Na$^+$ or H$^+$ to the ...
arxiv   +1 more source

How pollen tubes fight for food: the impact of sucrose carriers and invertases of Arabidopsis thaliana on pollen development and pollen tube growth

Frontiers in Plant Science, 2023
Pollen tubes of higher plants grow very rapidly until they reach the ovules to fertilize the female gametes. This growth process is energy demanding, however, the nutrition strategies of pollen are largely unexplored.
Jessica Seitz, Theresa Maria Reimann, Carolin Fritz, Carola Schröder, Johanna Knab, Walter Weber, Ruth Stadler   +6 more
doaj   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Investigation into the relationship between ethylene and sulfur assimilation in Arabidopsis thaliana and onion (Allium cepa L.) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science (with Honours) in Biochemistry at Massey University [PDF]

, 2006
The phytohormone ethylene (C2H4) mediates the adaptive responses of plants to various nutrient deficiencies including iron (Fe)-deficiency, phosphorus (P)-deficiency and potassium (K)-deficiency.
Sanggang, Fiona Ann
core  

Functional PTB phosphate transporters are present in streptophyte algae and early diverging land plants [PDF]

, 2017
International audienceTwo inorganic phosphate (Pi) uptake mechanisms operate in streptophytes and chloro-phytes, the two lineages of green plants. PHOSPHATE TRANSPORTER B (PTB) proteins are hypothesized to be the Na + /Pi symporters catalysing Pi uptake ...
Bonnot, Clémence, Breuninger, Holger, Champion, Clément, Colbalchini, Florine,, Dolan, Liam, Hetherington, Alexander,, Kelly, Steven, Lesly-Veillard, Alexis, Pinson, Benoit, Proust, Helene,   +9 more
core   +2 more sources

Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review

Chronic Diseases and Translational Medicine, EarlyView.
PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi, Yunia Sribudiani, Steven Yulius Usman, Eric Ricardo Yonatan, Ahmedz Widiasta, Noormarina Indraswari, Ria Bandiara, Nanny N. M. Soetedjo   +7 more
wiley   +1 more source

Evolutionary Relationship between K+ Channels and Symporters [PDF]

Biophysical Journal, 1999
The hypothesis is presented that at least four families of putative K(+) symporter proteins, Trk and KtrAB from prokaryotes, Trk1,2 from fungi, and HKT1 from wheat, evolved from bacterial K(+) channel proteins. Details of this hypothesis are organized around the recently determined crystal structure of a bacterial K(+) channel: i.
Evert P. Bakker, Tatsunosuke Nakamura, Yili Hao, Stewart R. Durell, H. Robert Guy   +4 more
openaire   +3 more sources

Glucose Transport in Escherichia coli: From Basics to Transport Engineering

Microorganisms, 2023
Escherichia coli is the best-known model for the biotechnological production of many biotechnological products, including housekeeping and heterologous primary and secondary metabolites and recombinant proteins, and is an efficient biofactory model to ...
Ofelia E. Carreón-Rodríguez, Guillermo Gosset, Adelfo Escalante, Francisco Bolívar   +3 more
doaj   +1 more source

Light-induced transcriptional responses associated with proteorhodopsin-enhanced growth in a marine flavobacterium [PDF]

, 2011
Proteorhodopsin (PR) is a photoprotein that functions as a light-driven proton pump in diverse marine Bacteria and Archaea. Recent studies have suggested that PR may enhance both growth rate and yield in some flavobacteria when grown under nutrient ...
A Martinez, Asuncion Martinez, BL Taylor, CC Häse, Curtis R Young, Edward F DeLong, EF DeLong, FJ Stewart, FX Cunningham, G Armstrong, G Sabehi, H Futamata, H Tokuda, Hiroyuki Kimura, J McCarren, J McCarren, JD Storey, JL Spudich, JM González, JM Walter, JR de la Torre, K Izui, KC Keiler, L Gómez-Consarnau, LS Brown, M Gomelsky, M Reich, MA Moran, MB Eisen, N-U Frigaard, O Béjà, O Béjà, PP Gardner, PV Attwood, R Gillet, R Lami, S Jitrapakdee, SD Moore, SJ Giovannoni, U Stingl, V Anantharaman, Y Benjamini, Y Shi   +42 more
core   +1 more source