Results 91 to 100 of about 6,581,441 (342)
Pharmaceuticals, 2014 In patients with functional upper gastrointestinal disorders such as gastroesophageal reflux disease and functional dyspepsia, the presence of symptoms is thought to occur in the absence of any organic diseases and the mechanisms behind this remain ...
Muneki Igarashi +8 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Obsessive-Compulsive symptoms among clients attending psychiatric outpatients' clinic in Duhok
Medical Journal of Babylon, 2018 Background: Obsessive-compulsive disorder (OCD) is a neuropsychiatric illness, develops in childhood, and can result in considerable impairment to an individual's lifespan.
Salim Saadi Miho Alhakem +2 more
doaj +1 more source
Maternal depression and youth internalizing and externalizing symptomatology: severity and chronicity of past maternal depression and current maternal depressive symptoms [PDF]
, 2016 Maternal depression is a well-documented risk factor for youth depression, and taking into account its severity and chronicity may provide important insight into the degree of risk conferred.
Langer, David A. +2 more
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Tropical Medicine and Infectious Disease, 2020 To successfully eliminate human African trypanosomiasis (HAT), healthcare workers (HCWs) must maintain their diagnostic acuity to identify cases as the disease becomes rarer.
Jennifer J. Palmer +3 more
doaj +1 more source
Electrophysiological evidence for changes in attentional orienting and selection in functional somatic symptoms [PDF]
, 2018 Neurophysiology Objective: We investigated changes in attention mechanisms in people who report a high number of somatic symptoms which cannot be associated with a physical cause.
Forster, B., Jones, A., Karlinski, M.
core +2 more sources
Research Progress in the Early Warning of Chicken Diseases by Monitoring Clinical Symptoms [PDF]
, 2022 Pengguang He +6 more
openalex +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Vision-related symptoms as a clinical feature of chronic fatigue syndrome/myalgic encephalomyelitis? Evidence from the DePaul Symptom Questionnaire [PDF]
, 2013 Chronic Fatigue Syndrome (CFS) or Myalgic Encephalomyelitis (ME) is a debilitating disorder, affecting at least 250,000 people in the UK. Marked by debilitating fatigue, its aetiology is poorly understood and diagnosis controversial. A number of symptoms
Claire V Hutchinson +9 more
core +1 more source