Results 21 to 30 of about 256,017 (307)

Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance

npj Parkinson's Disease, 2022
The accumulation of α-synuclein (α-syn) in intracellular formations known as Lewy bodies (LBs) is associated with several neurodegenerative diseases including Parkinson’s disease and Lewy Body Dementia.
Cara L. Croft, Giavanna Paterno, Ava R. Vause, Lyla A. Rowe, Daniel H. Ryu, Marshall S. Goodwin, Corey A. Moran, Pedro E. Cruz, Benoit I. Giasson, Todd E. Golde   +9 more
doaj   +1 more source

Receptor-Dependent Endocytosis Mediates α-Synuclein Oligomer Transport Into Red Blood Cells

Frontiers in Aging Neuroscience, 2022
Detection of oligomeric α-synuclein (o-α-Syn) in red blood cells (RBCs) has been shown to be promising in diagnosing Parkinson’s disease and other synucleinopathies.
Wei Li, Wei Li, Junya Hu, Junya Hu, Xin Li, Xin Li, Zhe Lu, Zhe Lu, Xuying Li, Chaodong Wang, Chaodong Wang, Shun Yu, Shun Yu   +12 more
doaj   +1 more source

MPC/OC Code for: Learning with Muscles: Benefits for Data-Efficiency and Robustness in Anthropomorphic Tasks

, 2022
This code allows you reproduce the optimal control and model predictive control results of the paper: "Learning with Muscles: Benefits for Data-Efficiency and Robustness in Anthropomorphic Tasks" by Isabell Wochner, Pierre Schumacher, Georg Martius ...
Wochner, Isabell, Schmitt, Syn
core   +1 more source

Stochastic model of TCP SYN attacks / Stochastinis TCP SYN atakų modelis

Mokslas: Lietuvos Ateitis, 2011
A great proportion of essential services are moving into internet space making the threat of DoS attacks even more actual. To estimate the real risk of some kind of denial of service (DoS) attack in real world is difficult, but mathematical and software ...
Simona Ramanauskaitė, Antanas Čenys
doaj   +1 more source

Tanshinone IIA Regulates Synaptic Plasticity in Mg2+-Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway

Journal of Integrative Neuroscience
Background: Tanshinone IIA (TSIIA) is an element of the effective ingredients of Salvia miltiorrhiza Bunge (Labiatae), exhibits a significant therapeutic effect in brain neuroprotection.
Meile Ma, Xi Hua, Chen Jia, Nan Xiao, Li Zhang, Liming Wei, Haisheng Jiao   +6 more
doaj   +1 more source

Zadania ojca w świetle prawodawstwa pierwotnego Kościoła

Vox Patrum
Artykułu próbuje ukazać rolę ojca w świetle kanonów pierwotnego Kościoła, począwszy od początków chrześcijaństwa aż po rok 600. Chodzi o takie zagadnienia, jak odpowiedzialność ojca za wiarę i zbawienie dzieci, właściwe wychowanie potomstwa, ochronę ...
Dariusz Piasecki
doaj   +1 more source

Obraz chrześcijańskiego ojca w "Vita Constantini" Euzebiusza z Cezarei

Vox Patrum
Artykuł na podstawie twórczości Euzebiusza z Cezarei "De vita Constantini" przedstawia cesarza Konstantyna jako ojca. Pokazuje troskę cesarza o wychowanie swoich dzieci, przekaz wiary chrześcijańskiej, zapewnienie edukacji i przygotowanie do przejęcia ...
Dariusz Piasecki
doaj   +1 more source

The genera of Nematinae (Hymenoptera, Tenthredinidae)

Journal of Hymenoptera Research, 2014
Recent phylogenetic studies on Nematinae based on DNA sequences have shown extensive incongruencies with current nomenclature of genus-group taxa. Here, we expand previous DNA sequence datasets based on three genes (CoI, Cytb, and EF-1α), to include a ...
Marko Prous, Stephan M. Blank, Henri Goulet, Erik Heibo, Andrew Liston, Tobias Malm, Tommi Nyman, Stefan Schmidt, David Smith, Hege Vårdal, Matti Viitasaari, Veli Vikberg, Andreas Taeger   +12 more
doaj   +1 more source

Distinct Effects of Familial Parkinson’s Disease-Associated Mutations on α-Synuclein Phase Separation and Amyloid Aggregation

Biomolecules, 2023
The Lewy bodies and Lewy neurites are key pathological hallmarks of Parkinson’s disease (PD). Single-point mutations associated with familial PD cause α-synuclein (α-Syn) aggregation, leading to the formation of Lewy bodies and Lewy neurites.
Bingkuan Xu, Fengshuo Fan, Yunpeng Liu, Yinghui Liu, Lin Zhou, Haijia Yu   +5 more
doaj   +1 more source

Credo in Patrem: Paterological Elements in the Teaching of Benedict XVI

Wrocławski Przegląd Teologiczny
The aim of this article is to present the paterological elements in the teaching of Benedict XVI. These elements appear as relevant when the Pope discusses other truths of faith.
Aleksander Sosnowski
doaj   +1 more source