Results 51 to 60 of about 37,262 (199)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Interpreting high levels of unfolded Von Willebrand Factor in patients with the antiphospholipid syndrome

Frontiers in Immunology
IntroductionUnfolded Von Willebrand Factor (VWF) is increased in thrombotic pathologies such as myocardial infarction. Unfolded VWF mediates the binding of platelets without the need for collagen.
Romy de Laat-Kremers, Shengshi Huang, Shengshi Huang, Hugo ten Cate, Hugo ten Cate, Marisa Ninivaggi, Bas de Laat, Bas de Laat, Katrien Devreese, Katrien Devreese   +9 more
doaj   +1 more source

ALD‐Assisted VO2 for Memristor Application

Advanced Engineering Materials, EarlyView.
This work demonstrates a strategy for depositing VOx using thermal atomic layer deposition (ALD) followed by thermal annealing to synthesize VO2. The thin film and core/shell wire memristors exhibit excellent switching performance and are highly sensitive to ambient temperature.
Jun Peng, Daniel Hensel, Rakshith Venugopal, Lucas Rave, Colin Schormann, Sebastian Koch, Robert H. Blick, Robert Zierold   +7 more
wiley   +1 more source

Magnetic Field‐Assisted Conductive Nerve Guidance Conduit Enabling Peripheral Nerve Regeneration with Wireless Electrical Stimulation

Advanced Functional Materials, EarlyView.
This study introduces a conductive nerve guidance conduit integrated with wireless electrical stimulation through alternating magnetic fields, which induces currents and creates a supportive microenvironment for nerve regeneration. In vivo studies show that this approach significantly enhanced myelin restoration, gastrocnemius muscle regeneration ...
Shiheng Liu, Li‐Fang Zhu, Ming‐Wei Chang, Chao Li, Tingyu Wang, Rong Wang, Xinghao Yan, Baolin Wang   +7 more
wiley   +1 more source

Clustered synapses develop in distinct dendritic domains in visual cortex before eye opening

eLife
Synaptic inputs to cortical neurons are highly structured in adult sensory systems, such that neighboring synapses along dendrites are activated by similar stimuli.
Alexandra H Leighton, Juliette E Cheyne, Christian Lohmann   +2 more
doaj   +1 more source

Biomimetic Design of Biocompatible Neural Probes for Deep Brain Signal Monitoring and Stimulation: Super Static Interface for Immune Response‐Enhanced Contact

Advanced Functional Materials, EarlyView.
Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Seon Yeong Chae, Min Jae Kim, Ki Jun Yu, Hwa Kyoung Shin, Suck Won Hong   +7 more
wiley   +1 more source

Ultra‐Fast Non‐Volatile Resistive Switching Devices with Over 512 Distinct and Stable Levels for Memory and Neuromorphic Computing

Advanced Functional Materials, EarlyView.
A materials and device design concept that comprises a self‐assembled ultra‐thin epitaxial ion‐transporting layer, an amorphous oxide overcoat oxygen‐blocking layer, and a partial filament formed during an electroforming step is proposed for low‐current multilevel resistive switching devices.
Ming Xiao, Markus Hellenbrand, Nives Strkalj, Babak Bakhit, Zhuotong Sun, Nikolaos Barmpatsalos, Dovydas Joksas, Hongyi Dou, Zedong Hu, Ping Lu, Samip Karki, Sundar Kunwar, Jonathan D. Major, Aiping Chen, Haiyan Wang, Quanxi Jia, Adnan Mehonic, Judith L. MacManus‐Driscoll   +17 more
wiley   +1 more source

Transient Current Responses of Organic Electrochemical Transistors: Evaluating Ion Diffusion, Chemical Capacitance, and Series Elements

Advanced Functional Materials, EarlyView.
This work establishes a general theory of the current transient of ionic‐electronic transistors under a step of gate voltage. The dominant effect is a transient charging of the channel by diffusion of ions. The additional influence of electrolyte capacitance and resistance splits the fundamental time constant of diffusion into two different components.
Juan Bisquert, Nir Tessler
wiley   +1 more source

Characterisation of the Volatile Compounds and Key Odourants in Japanese Mandarins by Gas Chromatography–Mass Spectrometry and Gas Chromatography–Olfactometry

Separations
Japanese mandarins are becoming increasingly popular due to their pleasant aroma. The volatiles in four varieties of Japanese mandarins (Iyokan, Ponkan, Shiranui, and Unshiu mikan) were extracted by headspace solid-phase microextraction (HS-SPME) and ...
Lingyi Li, Rui Min Vivian Goh, Yunle Huang, Kim-Huey Ee, Aileen Pua, Daphne Tan, Shanbo Zhang, Lionel Jublot, Shao Quan Liu, Bin Yu   +9 more
doaj   +1 more source

An NMDA Receptor-Dependent Mechanism Underlies Inhibitory Synapse Development

Cell Reports, 2016
In the mammalian brain, GABAergic synaptic transmission provides inhibitory balance to glutamatergic excitatory drive and controls neuronal output. The molecular mechanisms underlying the development of GABAergic synapses remain largely unclear. Here, we
Xinglong Gu, Liang Zhou, Wei Lu
doaj   +1 more source