Results 71 to 80 of about 372,410 (315)
An Oxide Schottky Junction Artificial Optoelectronic Synapse.
The rapid development of artificial intelligence techniques and future advanced robot systems sparks emergent demand on the accurate perception and understanding of the external environments via visual sensing systems that can co-locate the self-adaptive
Shuang Gao +9 more
semanticscholar +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Synaptic transmission between neurons is governed by a cascade of stochastic calcium ion reaction–diffusion events within nerve terminals leading to vesicular release of neurotransmitter.
Maria Reva +2 more
doaj +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
The Role of Non-Destructive Testing of Composite Materials for Aerospace Applications
This review examines the essential application of non-destructive testing (NDT) techniques in assessing the integrity and damage of composite materials used in aerospace engineering, focusing on polymer matrix composites (PMCs), metal matrix composites ...
Thiago Luiz Lara Oliveira +3 more
doaj +1 more source
Stretchable organic optoelectronic sensorimotor synapse
We developed a stretchable organic optoelectronic sensorimotor synapse to mimic a biological optical sensory nervous system. Emulation of human sensory and motor functions becomes a core technology in bioinspired electronics for next-generation ...
Yeongjun Lee +11 more
semanticscholar +1 more source
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Procoagulant off-target effect of the direct oral anticoagulant reversal agent Andexanet alfa
: Patients with hemorrhage after treatment with direct oral anticoagulants (DOACs) are saved from hematoma expansion by administration of Andexanet alfa, a modified factor Xa analog.
Ischa M. S. Hoornstra +9 more
doaj +1 more source
Optically Stimulated Artificial Synapse Based on Layered Black Phosphorus.
The translation of biological synapses onto a hardware platform is an important step toward the realization of brain-inspired electronics. However, to mimic biological synapses, devices till-date continue to rely on the need for simultaneously altering ...
Taimur Ahmed +7 more
semanticscholar +1 more source

