Results 61 to 70 of about 402,240 (289)
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Scientific Reports, 2021 Synaptic transmission between neurons is governed by a cascade of stochastic calcium ion reaction–diffusion events within nerve terminals leading to vesicular release of neurotransmitter.
Maria Reva +2 more
doaj +1 more source
Synaptic Release Potentiation at Aging Auditory Ribbon Synapses
Frontiers in Aging Neuroscience, 2021 Age-related hidden hearing loss is often described as a cochlear synaptopathy that results from a progressive degeneration of the inner hair cell (IHC) ribbon synapses.
Thibault Peineau +7 more
doaj +1 more source
Hardware design of LIF with Latency neuron model with memristive STDP synapses
, 2017 In this paper, the hardware implementation of a neuromorphic system is presented. This system is composed of a Leaky Integrate-and-Fire with Latency (LIFL) neuron and a Spike-Timing Dependent Plasticity (STDP) synapse.
Acciarito, Simone +7 more
core +1 more source
CMOS current-mode chaotic neurons [PDF]
, 1994 This paper presents two nonlinear CMOS current-mode circuits that implement neuron soma equations for chaotic neural networks, and another circuit to realize programmable current-mode synapse using CMOS-compatible BJT's.
Delgado Restituto, Manuel +1 more
core +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Thrombin generation remains stable in frozen plasma over long-term storage
Thrombosis UpdateBackground: The ST Genesia is a fully automated thrombin generation (TG) device. Measuring TG can be useful for medical purposes as it is an indicator for the bleeding or thrombotic risk of a patient.
A. Carlo +3 more
doaj +1 more source
A CMOS Spiking Neuron for Brain-Inspired Neural Networks with Resistive Synapses and In-Situ Learning [PDF]
, 2015 Nanoscale resistive memories are expected to fuel dense integration of electronic synapses for large-scale neuromorphic system. To realize such a brain-inspired computing chip, a compact CMOS spiking neuron that performs in-situ learning and computing ...
Balagopal, Sakkarapani +3 more
core +3 more sources
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Spin-Based Neuron Model with Domain Wall Magnets as Synapse
, 2012 We present artificial neural network design using spin devices that achieves ultra low voltage operation, low power consumption, high speed, and high integration density.
Augustine, Charles +3 more
core +1 more source