Results 61 to 70 of about 372,410 (315)

Contrast-Enhanced OCT for Damage Detection in Polymeric Resins Embedded with Metallic Nanoparticles via Surface Plasmon Resonance

NDT - Journal of Non-Destructive Testing
Nanoparticle-embedded polymeric materials are an important subject in advanced structural applications due to their advantageous combination of low weight and high mechanical performance.
Maha Hadded, Thiago Luiz Lara Oliveira, Olivier Debono, Emilien Bourdon, Alan Jean-Marie   +4 more
doaj   +1 more source

The synapse in traumatic brain injury

Brain : a journal of neurology, 2020
Traumatic brain injury is a leading cause of death and disability and is a risk factor for dementia later in life. Jamjoom et al. review the role of the synapse in TBI pathophysiology with a focus on the confluence of secondary injury processes including
A. Jamjoom, J. Rhodes, P. Andrews, S. Grant   +3 more
semanticscholar   +1 more source

Autophagy at the synapse [PDF]

Neuroscience Letters, 2019
As the sites of communication between neurons, synapses depend upon precisely regulated protein-protein interactions to support neurotransmitter release and reception. Moreover, neuronal synapses typically exist great distances (i.e. up to meters) away from cell bodies, which are the sources of new proteins and the major sites of protein degradation ...
Veronica Birdsall, Clarissa L. Waites
openaire   +2 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Ingredients, Processing, and Fermentation: Addressing the Organoleptic Boundaries of Plant-Based Dairy Analogues

Foods, 2022
Consumer interest and research in plant-based dairy analogues has been growing in recent years because of increasingly negative implications of animal-derived products on human health, animal wellbeing, and the environment.
Aileen Pua, Vivien Chia Yen Tang, Rui Min Vivian Goh, Jingcan Sun, Benjamin Lassabliere, Shao Quan Liu   +5 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development

Frontiers in Cellular Neuroscience, 2019
In the adult brain GABAA receptors (GABAARs) mediate the majority of synaptic inhibition that provides inhibitory balance to excitatory drive and controls neuronal output.
Jingjing Duan, Jingjing Duan, Saurabh Pandey, Tianming Li, David Castellano, Xinglong Gu, Jun Li, Qingjun Tian, Wei Lu   +8 more
doaj   +1 more source

Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling

Nature Neuroscience, 2019
Microglia rapidly respond to changes in neural activity and inflammation to regulate synaptic connectivity. The extracellular signals, particularly neuron-derived molecules, that drive these microglial functions at synapses remain a key open question ...
Georgia Gunner, Lucas Cheadle, Kasey M. Johnson, Pinar Ayata, Ana Badimon, Erica Mondo, A. Nagy, Liwang Liu, S. Bemiller, Ki-Wook Kim, S. Lira, B. Lamb, A. Tapper, R. Ransohoff, M. Greenberg, A. Schaefer, Dorothy P. Schafer   +16 more
semanticscholar   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Thrombin generation remains stable in frozen plasma over long-term storage

Thrombosis Update
Background: The ST Genesia is a fully automated thrombin generation (TG) device. Measuring TG can be useful for medical purposes as it is an indicator for the bleeding or thrombotic risk of a patient.
A. Carlo, R. de Laat-Kremers, B. de Laat, M. Ninivaggi   +3 more
doaj   +1 more source