Results 31 to 40 of about 402,240 (289)

Thrombin generation in low plasma volumes

open access: yesThrombosis Journal, 2018
Accurate thrombin generation determination by calibrated automated thrombinography can be sustained when reducing the plasma and reagent volumes up to half, but not for higher reductions or plasma dilutions.
Saartje Bloemen   +2 more
doaj   +1 more source

Absence of synaptic regulation by phosducin in retinal slices. [PDF]

open access: yes, 2013
Phosducin is an abundant photoreceptor protein that binds G-protein βγ subunits and plays a role in modulating synaptic transmission at photoreceptor synapses under both dark-adapted and light-adapted conditions in vivo.
Arshavsky, Vadim Y   +2 more
core   +8 more sources

Synapse: Synthetic Application Profiler and Emulator

open access: yes, 2016
We introduce Synapse motivated by the needs to estimate and emulate workload execution characteristics on high-performance and distributed heterogeneous resources.
Jha, Shantenu, Merzky, Andre
core   +1 more source

Platelet Activation Pathways Controlling Reversible Integrin αIIbβ3 Activation

open access: yesTH Open
Background Agonist-induced platelet activation, with the integrin αIIbβ3 conformational change, is required for fibrinogen binding. This is considered reversible under specific conditions, allowing a second phase of platelet aggregation.
Jinmi Zou   +8 more
doaj   +1 more source

Coagulation parameters predict COVID-19-related thrombosis in a neural network with a positive predictive value of 98%

open access: yesFrontiers in Immunology, 2022
Thrombosis is a major clinical complication of COVID-19 infection. COVID-19 patients show changes in coagulation factors that indicate an important role for the coagulation system in the pathogenesis of COVID-19.
Romy de Laat-Kremers   +8 more
doaj   +1 more source

Modeling Maintenance of Long-Term Potentiation in Clustered Synapses, Long-Term Memory Without Bistability [PDF]

open access: yes, 2015
Memories are stored, at least partly, as patterns of strong synapses. Given molecular turnover, how can synapses maintain strong for the years that memories can persist?
Smolen, Paul
core   +4 more sources

Thrombomodulin is a stronger indicator of combined oral contraceptives-induced activated protein C pathway resistance in the thrombin generation test than activated protein C

open access: yesFrontiers in Cardiovascular Medicine
BackgroundThe mechanism by which combined oral contraceptives (COCs) lead to hypercoagulation is not fully understood, although activated protein C (APC) pathway resistance has been implicated.
Marisa Ninivaggi   +6 more
doaj   +1 more source

Correction to: Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1

open access: yesBMC Cancer, 2019
Following publication of the original article [1], the authors have re-evaluated the authorship for this article. The updated author group is:
Ho-Keun Kwon   +10 more
doaj   +1 more source

The Immunological Synapse [PDF]

open access: yesCancer Immunology Research, 2003
AbstractThe molecular interactions underlying regulation of the immune response take place in a nanoscale gap between T cells and antigen-presenting cells, termed the immunological synapse. If these interactions are regulated appropriately, the host is defended against a wide range of pathogens and deranged host cells.
openaire   +6 more sources

The Innovative Medicines Initiative neurodegeneration portfolio: From individual projects to collaborative networks

open access: yesFrontiers in Neurology, 2022
The IMI public-private partnership between the European Commission and the European Federation of Pharmaceutical Industries and Associations (EFPIA) was launched in 2008 with an initial budget of €2 billion.
Diana O'Rourke   +9 more
doaj   +1 more source

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