Results 11 to 20 of about 402,240 (289)

DISC1 is needed for the organization of cellular components at the immunological synapse. [PDF]

open access: yes, 2019
T-cells carry out their immune functions through receptor-based recognition and adhesion to target cells. The cell-cell junction that is created from this connection is known as the immunological synapse (IS); a cellular structure composed of organized ...
Ramakrishnan, Adarsh
core   +1 more source

Probabilistic Fluorescence-Based Synapse Detection [PDF]

open access: yes, 2016
Brain function results from communication between neurons connected by complex synaptic networks. Synapses are themselves highly complex and diverse signaling machines, containing protein products of hundreds of different genes, some in hundreds of ...
Aguerrebere, Cecilia   +7 more
core   +4 more sources

A Hypoxic Environment Attenuates Exercise-Induced Procoagulant Changes Due to Decreased Platelet Activation

open access: yesTH Open, 2019
Introduction Although physical exercise is protective against cardiovascular disease, it can also provoke sudden cardiac death (exercise paradox).
Cécile H. Kicken   +6 more
doaj   +1 more source

Synaptic basis of a sub-second representation of time in a neural circuit model

open access: yesNature Communications, 2022
Neural circuit dynamics are thought to drive temporally precise actions. Here, the authors used a theoretical approach to show that synapses endowed with diverse short-term plasticity can act as tunable timers sufficient to generate rich neural dynamics.
A. Barri   +3 more
doaj   +1 more source

Increased BMI and Blood Lipids Are Associated With a Hypercoagulable State in the Moli-sani Cohort

open access: yesFrontiers in Cardiovascular Medicine, 2022
The coagulation system can be assessed by the thrombin generation (TG) assay, and increased TG peak height, endogenous thrombin potential (ETP), and velocity index are associated with an increased risk of thrombosis. Obesity had been reported to increase
Romy de Laat-Kremers   +21 more
doaj   +1 more source

Synapses immunologiques et synapses neuronales [PDF]

open access: yesmédecine/sciences, 2003
Les systemes nerveux et immunitaire ont en commun de constituer dans l’organisme des reseaux complexes de cellules en interaction. Dans ces reseaux transitent en permanence d’enormes quantites d’informations, codees de facon tres differente dans les deux cas. Ces informations doivent en particulier circuler de cellule en cellule.
Trautmann, Alain   +3 more
openaire   +2 more sources

Tailoring the effect of antithrombin-targeting therapy in haemophilia A using in silico thrombin generation

open access: yesScientific Reports, 2021
Factor (F) VIII deficiency causes bleeding in haemophilia A patients because of the reduced formation of procoagulant enzyme thrombin, which is needed to make the blood clot.
Romy M. W. de Laat-Kremers   +4 more
doaj   +1 more source

Astrocytic Ephrin-B1 Regulates Synapse Remodeling Following Traumatic Brain Injury. [PDF]

open access: yes, 2016
Traumatic brain injury (TBI) can result in tissue alterations distant from the site of the initial injury, which can trigger pathological changes within hippocampal circuits and are thought to contribute to long-term cognitive and neuropsychological ...
Ethell, Iryna M   +5 more
core   +3 more sources

Developmental Understanding of Death and Grief Among Children During COVID-19 Pandemic: Application of Bronfenbrenner's Bioecological Model

open access: yesFrontiers in Psychiatry, 2021
COVID-19 Pandemic has influenced death-related attitudes and understanding during the childhood development leading to a life-long impact. Factors like pandemic-related movement restrictions, school closures, and parents' stay-at-home have exposed ...
Aisha Sanober Chachar   +2 more
doaj   +1 more source

Robustness and Enhancement of Neural Synchronization by Activity-Dependent Coupling [PDF]

open access: yes, 2002
We study the synchronization of two model neurons coupled through a synapse having an activity-dependent strength. Our synapse follows the rules of Spike-Timing Dependent Plasticity (STDP).
C. Bell   +10 more
core   +2 more sources

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