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The History of the Synapse [PDF]

open access: yesThe Anatomical Record, 2020
ABSTRACTWhy did I choose this particular topic for my lecture rather than the history of neuroscience or the history of the neuron? Simply because I believe that every disciple has the obligation to pay homage to their mentors once in their lifetime. My formation as a neuroscientist involved three such mentors spanned across three countries.
openaire   +2 more sources

Differential segregation in a cell-cell contact interface: the dynamics of the immunological synapse [PDF]

open access: yes, 2002
Receptor-ligand couples in the cell-cell contact interface between a T cell and an antigen-presenting cell form distinct geometric patterns and undergo spatial rearrangement within the contact interface.
Nigel John Burroughs   +3 more
core   +1 more source

Developmental Understanding of Death and Grief Among Children During COVID-19 Pandemic: Application of Bronfenbrenner's Bioecological Model

open access: yesFrontiers in Psychiatry, 2021
COVID-19 Pandemic has influenced death-related attitudes and understanding during the childhood development leading to a life-long impact. Factors like pandemic-related movement restrictions, school closures, and parents' stay-at-home have exposed ...
Aisha Sanober Chachar   +2 more
doaj   +1 more source

MRamirez1414/Cochlear-ribbon-synapse-maturation-requires-Nlgn1-and-Nlgn3: Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3

open access: yes, 2022
Code associated with Cochlear ribbon synapse maturation requires Nlgn1 and ...
MRamirez1414
core   +1 more source

The Value of Brain Imaging and Electrophysiological Testing for Early Screening of Autism Spectrum Disorder: A Systematic Review

open access: yesFrontiers in Neuroscience, 2022
Given the significance of validating reliable tests for the early detection of autism spectrum disorder (ASD), this systematic review aims to summarize available evidence of neuroimaging and neurophysiological changes in high-risk infants to improve ASD ...
Cullen Clairmont   +7 more
doaj   +1 more source

Effects of Plasmin on von Willebrand Factor and Platelets: A Narrative Review

open access: yesTH Open, 2018
Plasmin is the major fibrinolytic protease responsible for dissolving thrombi by cleavage of its primary substrate fibrin. In addition, emerging evidence points to other roles of plasmin: (1) as a back-up for ADAMTS13 in proteolysis of ultra-large von ...
Lisa N. van der Vorm   +3 more
doaj   +1 more source

Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling

open access: yesNature Communications, 2020
NMDA receptor-dependent long-term depression (NMDAR-LTD) is a form of synaptic plasticity mediated by reduced recycling of AMPA receptors to the plasma membrane.
Hongmei Shen   +4 more
doaj   +1 more source

Thrombin generation in low plasma volumes

open access: yesThrombosis Journal, 2018
Accurate thrombin generation determination by calibrated automated thrombinography can be sustained when reducing the plasma and reagent volumes up to half, but not for higher reductions or plasma dilutions.
Saartje Bloemen   +2 more
doaj   +1 more source

IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α

open access: yesNature Communications, 2017
Molecular mechanisms regulating the development of inhibitory synapses are poorly understood. Here the authors show that IgSF21 interacts with neurexin2α to induce presynaptic differentiation of inhibitory synapses, and that mice lacking IgSF21 exhibit ...
Yuko Tanabe   +6 more
doaj   +1 more source

Feed-forward recruitment of electrical synapses enhances synchronous spiking in the mouse cerebellar cortex

open access: yeseLife, 2020
In the cerebellar cortex, molecular layer interneurons use chemical and electrical synapses to form subnetworks that fine-tune the spiking output of the cerebellum.
Andreas Hoehne   +2 more
doaj   +1 more source

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